Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MN088_RS10000 Genome accession   NZ_CP093413
Coordinates   1987928..1990006 (-) Length   692 a.a.
NCBI ID   WP_003130812.1    Uniprot ID   Q9CI06
Organism   Lactococcus lactis strain AH1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1982928..1995006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MN088_RS09970 (MN088_09970) - 1983208..1983501 (-) 294 WP_021214901.1 ATP-binding cassette domain-containing protein -
  MN088_RS09975 (MN088_09975) - 1983570..1983968 (-) 399 WP_225308036.1 hypothetical protein -
  MN088_RS09980 (MN088_09980) fabI 1984239..1984991 (-) 753 WP_010905443.1 enoyl-ACP reductase FabI -
  MN088_RS09985 (MN088_09985) fabZ 1985267..1985722 (+) 456 WP_003130498.1 3-hydroxyacyl-ACP dehydratase FabZ -
  MN088_RS09990 (MN088_09990) - 1985790..1986908 (-) 1119 WP_021214900.1 M20 family metallopeptidase -
  MN088_RS09995 (MN088_09995) - 1986923..1987732 (-) 810 WP_010905441.1 ABC transporter substrate-binding protein -
  MN088_RS10000 (MN088_10000) uvrB 1987928..1990006 (-) 2079 WP_003130812.1 excinuclease ABC subunit UvrB Machinery gene
  MN088_RS10005 (MN088_10005) - 1990017..1990478 (-) 462 WP_306171264.1 RNA pyrophosphohydrolase -
  MN088_RS10010 (MN088_10010) def 1990626..1991261 (+) 636 WP_003130816.1 peptide deformylase -
  MN088_RS10015 (MN088_10015) gap 1991404..1992417 (-) 1014 WP_003130818.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  MN088_RS10020 (MN088_10020) - 1992590..1993060 (+) 471 WP_010905440.1 Rrf2 family transcriptional regulator -

Sequence

Protein


Download         Length: 692 a.a.        Molecular weight: 79131.46 Da        Isoelectric Point: 4.5652

>NTDB_id=572216 MN088_RS10000 WP_003130812.1 1987928..1990006(-) (uvrB) [Lactococcus lactis strain AH1]
MAIERITDNKFELVSKYEPAGDQGEAIAELVDNIENGEKAQILRGATGTGKTYTMSQVIARTGKPTLVMAHNKTLAGQLY
SEFKEFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEY
QDSVVSLRPGQEISRDQLLNDLVGIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRIREIEVLTGQV
LGEVDHLAIFPATHFMTNDDRMEESIAKIEAELEEQLKVFRSEGKLLEAQRLEQRTNYDIEMLREMGYCNGVENYSRHMD
GREEGEPPYTLLDFFPDDFMIMIDESHMTMGQVKGMYNGDRARKEMLCNYGFRLPSALDNRPLKREEFESHVHQIVYVSA
TPGDYEMEQTDTIVEQIIRPTGLLDPVVEVRPMMGQIDDLVGEIHKRAEKNERVFVTTLTKKMSEDLTAYFKEMGIKVKY
MHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVILYSD
MAKALDENDPVDKEILDSGYYTEYEGQKYKITRSMKHAMDETARRREIQMAYNEEHGITPQTIKKEIRDLIAITKKTDSG
EIEEVDASAMTKKERKALVKKLEKEMQQAASALDFEGAAQLRDMVLELRAMD

Nucleotide


Download         Length: 2079 bp        

>NTDB_id=572216 MN088_RS10000 WP_003130812.1 1987928..1990006(-) (uvrB) [Lactococcus lactis strain AH1]
ATGGCTATAGAAAGAATAACAGATAATAAATTTGAACTTGTTTCAAAATATGAGCCAGCCGGTGACCAAGGTGAGGCGAT
TGCTGAGTTAGTAGATAATATTGAGAATGGGGAAAAAGCTCAAATTTTACGTGGAGCAACAGGAACAGGGAAAACTTACA
CCATGAGTCAAGTGATTGCACGGACAGGTAAACCTACTCTTGTTATGGCTCATAATAAAACACTGGCTGGTCAATTATAC
AGTGAATTTAAAGAGTTTTTTCCAAATAATGCAGTCGAGTATTTCGTATCCTACTATGATTATTATCAACCCGAAGCCTA
TGTTCCAAGTTCTGACACCTATATTGAAAAAGACAGTTCGGTCAATGATGAAATTGATAAATTGCGTCATAGTGCGACCT
CAAGCTTATTGGAACGTAATGATGTGATTGTTGTGGCCTCAGTTTCTTGTATTTATGGATTGGGTTCACCCAAAGAGTAT
CAAGATTCGGTGGTTTCATTGCGCCCAGGTCAAGAAATTTCTCGTGACCAACTTTTAAATGATTTGGTAGGAATTCAATT
TGAGCGAAATGATATTGACTTTCAACGGGGCTGTTTCCGAGTTCGCGGGGATGTTGTAGAAGTTTTTCCAGCCTCTCGTG
ATGAACATGCCTTTCGTGTTGAATTTTTCGGTGATGAAATTGACCGTATCCGTGAAATTGAAGTTTTGACCGGACAAGTT
TTAGGTGAAGTAGACCATTTGGCAATTTTCCCAGCGACACATTTCATGACAAATGATGACCGTATGGAAGAATCAATTGC
CAAGATAGAAGCAGAATTAGAAGAACAATTAAAAGTTTTCCGCTCAGAAGGAAAACTTCTTGAGGCTCAACGTTTAGAAC
AAAGAACCAACTACGATATCGAAATGCTCCGTGAAATGGGTTATTGTAATGGGGTCGAAAACTATTCACGTCATATGGAT
GGGCGCGAGGAAGGCGAACCTCCGTATACTTTACTTGATTTCTTTCCTGATGATTTCATGATTATGATTGATGAATCACA
CATGACAATGGGGCAAGTAAAAGGAATGTATAACGGTGACAGAGCCCGTAAAGAAATGCTTTGTAATTATGGATTCCGCC
TGCCTTCAGCCCTCGATAACCGTCCTTTAAAAAGAGAAGAATTTGAAAGTCATGTGCATCAAATTGTTTATGTTTCAGCA
ACCCCTGGGGATTATGAGATGGAGCAGACCGATACCATTGTTGAACAAATTATTCGTCCAACAGGTCTATTAGATCCTGT
CGTAGAAGTTCGACCAATGATGGGACAAATCGATGATTTAGTTGGTGAAATTCATAAACGAGCTGAGAAAAACGAACGAG
TATTCGTCACGACTTTGACTAAAAAGATGTCAGAAGATTTAACTGCCTATTTCAAGGAAATGGGGATAAAAGTTAAATAT
ATGCACTCGGATATCAAAACATTAGAACGAACCGAAATTATTCGGGATTTGCGTTTAGGAGTCTTTGATGTTCTGGTGGG
AATAAATCTGCTTCGCGAAGGGATTGACGTGCCAGAAGTTTCTTTAGTCGCGATTTTGGATGCTGATAAAGAAGGATTTT
TACGTAATGAGCGTGGCTTGATTCAGACCATTGGTCGTGCAGCACGTAATAGTGAAGGTCATGTTATTCTTTATTCTGAT
ATGGCTAAAGCCCTTGATGAAAATGATCCTGTGGATAAAGAAATCTTAGATAGTGGTTATTATACAGAATACGAGGGTCA
AAAGTATAAAATAACGCGTTCAATGAAACATGCGATGGATGAAACAGCCCGTCGGCGTGAAATTCAAATGGCTTATAATG
AAGAACATGGAATCACACCTCAAACGATCAAAAAAGAAATTCGTGATTTGATTGCCATTACTAAGAAAACTGATTCTGGT
GAGATTGAAGAAGTTGATGCAAGTGCGATGACTAAGAAAGAACGTAAAGCATTAGTCAAAAAACTTGAAAAAGAAATGCA
ACAAGCGGCTAGCGCCCTCGACTTTGAAGGAGCTGCTCAGTTACGTGATATGGTATTAGAATTACGTGCAATGGATTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(165-255)

Helicase conserved C-terminal domain (Helicase_C)

(441-550)

Type III restriction enzyme, res subunit (ResIII)

(19-144)

Ultra-violet resistance protein B (UvrB)

(590-628)

UvrB/uvrC motif (UVR)

(657-690)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CI06

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

82.029

99.711

0.818
  uvrB Streptococcus pneumoniae D39

82.029

99.711

0.818
  uvrB Streptococcus pneumoniae TIGR4

81.884

99.711

0.816