Detailed information NTG0571638

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: KH238_RS15075
• Genome accession: NZ_CP076045
• Coordinates: 3111055..3112218 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain VCN56
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3106055..3117218

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KH238_RS15045 (KH238_15045)	-	3106319..3106738 (-)	420	WP_007407479.1	TIGR03826 family flagellar region protein	-
KH238_RS15050 (KH238_15050)	comFC	3106812..3107501 (-)	690	WP_197061611.1	phosphoribosyltransferase family protein	Machinery gene
KH238_RS15055 (KH238_15055)	-	3107507..3107791 (-)	285	WP_007407481.1	competence protein ComFB	-
KH238_RS15060 (KH238_15060)	comFA	3107849..3109234 (-)	1386	WP_007407482.1	DEAD/DEAH box helicase	Machinery gene
KH238_RS15065 (KH238_15065)	-	3109343..3110191 (-)	849	WP_007407483.1	DegV family protein	-
KH238_RS15070 (KH238_15070)	degU	3110289..3110978 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
KH238_RS15075 (KH238_15075)	degS	3111055..3112218 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
KH238_RS15080 (KH238_15080)	-	3112441..3113088 (+)	648	WP_007407485.1	YigZ family protein	-
KH238_RS15085 (KH238_15085)	-	3113093..3114313 (+)	1221	WP_032867080.1	LCP family protein	-
KH238_RS15090 (KH238_15090)	-	3114412..3115488 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
KH238_RS15095 (KH238_15095)	-	3115621..3116817 (-)	1197	WP_032867083.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=571638 KH238_RS15075 WP_007407484.1 3111055..3112218(-) (degS) [Bacillus velezensis strain VCN56]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=571638 KH238_RS15075 WP_007407484.1 3111055..3112218(-) (degS) [Bacillus velezensis strain VCN56]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCTTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
ATCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951