Detailed information NTG0571293

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: MLA23_RS03505
• Genome accession: NZ_CP093317
• Coordinates: 723631..724290 (-)
• Length: 219 a.a.
• NCBI ID: WP_263852507.1
• Uniprot ID: -
• Organism: Escherichia coli strain HUM3355
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 718631..729290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MLA23_RS03480 (MLA23_03480)	parE	718722..720614 (+)	1893	WP_000195296.1	DNA topoisomerase IV subunit B	-
MLA23_RS03485 (MLA23_03485)	ygiN	720662..720976 (-)	315	WP_000958598.1	putative quinol monooxygenase	-
MLA23_RS03490 (MLA23_03490)	mdaB	721007..721588 (-)	582	WP_000065430.1	NADPH:quinone oxidoreductase MdaB	-
MLA23_RS03495 (MLA23_03495)	ygiZ	721907..722239 (+)	333	WP_000917684.1	DUF2645 family protein	-
MLA23_RS03500 (MLA23_03500)	qseC	722285..723634 (-)	1350	WP_000673402.1	quorum sensing histidine kinase QseC	-
MLA23_RS03505 (MLA23_03505)	ciaR	723631..724290 (-)	660	WP_263852507.1	quorum sensing response regulator transcription factor QseB	Regulator
MLA23_RS03510 (MLA23_03510)	ygiW	724442..724834 (+)	393	WP_000712658.1	OB fold stress tolerance protein YgiW	-
MLA23_RS03515 (MLA23_03515)	ygiV	724887..725369 (+)	483	WP_000183505.1	AraC family transcriptional regulator	-
MLA23_RS03520 (MLA23_03520)	mqsR	725574..725705 (+)	132	Protein_690	type II toxin-antitoxin system toxin MqsR	-
MLA23_RS03525 (MLA23_03525)	-	725722..726420 (-)	699	Protein_691	IS1-like element IS1A family transposase	-
MLA23_RS03530 (MLA23_03530)	mqsR	726475..726648 (+)	174	Protein_692	type II toxin-antitoxin system toxin MqsR	-
MLA23_RS03535 (MLA23_03535)	mqsA	726650..727045 (+)	396	WP_000650107.1	type II toxin-antitoxin system antitoxin MqsA	-
MLA23_RS03540 (MLA23_03540)	ygiS	727178..728785 (+)	1608	WP_064221462.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24687.67 Da
• Isoelectric Point: 7.4216

>NTDB_id=571293 MLA23_RS03505 WP_263852507.1 723631..724290(-) (ciaR) [Escherichia coli strain HUM3355]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTKGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide

• Length: 660 bp

>NTDB_id=571293 MLA23_RS03505 WP_263852507.1 723631..724290(-) (ciaR) [Escherichia coli strain HUM3355]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACAAAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-216)

• Response regulator receiver domain (Response_reg) (3-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	38.326	100	0.397
ciaR	Streptococcus pneumoniae D39	38.326	100	0.397
ciaR	Streptococcus pneumoniae R6	38.326	100	0.397
ciaR	Streptococcus pneumoniae TIGR4	38.326	100	0.397
ciaR	Streptococcus mutans UA159	35.874	100	0.365