Detailed information NTG0057081

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: M1GAS476_RS02285
• Genome accession: NC_020540
• Coordinates: 434167..435168 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes M1 476
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 429167..440168

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M1GAS476_RS02260 (M1GAS476_0475)	-	429841..430524 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
M1GAS476_RS02265 (M1GAS476_0476)	-	430735..431661 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
M1GAS476_RS02270 (M1GAS476_0477)	-	431806..432183 (-)	378	WP_002985686.1	VOC family protein	-
M1GAS476_RS02275 (M1GAS476_0478)	-	432194..432859 (-)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
M1GAS476_RS02280 (M1GAS476_0479)	-	432908..433993 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
M1GAS476_RS02285 (M1GAS476_0480)	ccpA	434167..435168 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
M1GAS476_RS02290 (M1GAS476_0481)	-	435299..436297 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
M1GAS476_RS02295 (M1GAS476_0482)	-	436299..437633 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
M1GAS476_RS02300 (M1GAS476_0483)	thrS	438055..439998 (+)	1944	WP_010921984.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=57081 M1GAS476_RS02285 WP_002985680.1 434167..435168(+) (ccpA) [Streptococcus pyogenes M1 476]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=57081 M1GAS476_RS02285 WP_002985680.1 434167..435168(+) (ccpA) [Streptococcus pyogenes M1 476]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559