Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MM431_RS10045 Genome accession   NZ_CP093068
Coordinates   2075391..2076047 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain BR1220     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2070391..2081047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MM431_RS10015 (MM431_10015) dcyD 2071271..2072257 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  MM431_RS10020 (MM431_10020) tcyL 2072272..2072940 (+) 669 WP_241468771.1 cystine ABC transporter permease -
  MM431_RS10025 (MM431_10025) tcyN 2072937..2073689 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MM431_RS10030 (MM431_10030) sdiA 2073919..2074641 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  MM431_RS10035 (MM431_10035) yecF 2074708..2074932 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  MM431_RS10040 (MM431_10040) yecU 2074919..2075095 (-) 177 WP_001326718.1 protein YecU -
  MM431_RS26110 - 2075178..2075249 (-) 72 Protein_1982 transcriptional regulator -
  MM431_RS10045 (MM431_10045) letA 2075391..2076047 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MM431_RS10050 (MM431_10050) uvrC 2076044..2077876 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  MM431_RS10055 (MM431_10055) pgsA 2077933..2078481 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MM431_RS10075 (MM431_10075) - 2079475..2079756 (+) 282 WP_071527557.1 hypothetical protein -
  MM431_RS10080 (MM431_10080) - 2079946..2080086 (-) 141 WP_000078916.1 Hok/Gef family protein -
  MM431_RS10085 (MM431_10085) - 2080278..2080537 (-) 260 Protein_1988 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=570543 MM431_RS10045 WP_000611335.1 2075391..2076047(+) (letA) [Escherichia coli strain BR1220]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=570543 MM431_RS10045 WP_000611335.1 2075391..2076047(+) (letA) [Escherichia coli strain BR1220]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486