Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LJF86_RS20850 Genome accession   NZ_CP093011
Coordinates   4354996..4355586 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 131     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4349996..4360586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LJF86_RS20825 (LJF86_20825) ysdE 4351081..4351155 (+) 75 WP_211180519.1 protein YsdE -
  LJF86_RS20830 (LJF86_20830) ivbL 4351400..4351498 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  LJF86_RS20835 (LJF86_20835) ilvB 4351604..4353292 (+) 1689 WP_000168502.1 acetolactate synthase large subunit -
  LJF86_RS20840 (LJF86_20840) ilvN 4353296..4353586 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  LJF86_RS20845 (LJF86_20845) - 4353652..4354512 (-) 861 WP_000556883.1 DUF6708 domain-containing protein -
  LJF86_RS20850 (LJF86_20850) letA 4354996..4355586 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  LJF86_RS20855 (LJF86_20855) uhpB 4355586..4357088 (+) 1503 WP_241461229.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  LJF86_RS20860 (LJF86_20860) uhpC 4357098..4358417 (+) 1320 WP_001296565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  LJF86_RS20865 (LJF86_20865) uhpT 4358555..4359946 (+) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=569110 LJF86_RS20850 WP_000633668.1 4354996..4355586(+) (letA) [Escherichia coli strain 131]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=569110 LJF86_RS20850 WP_000633668.1 4354996..4355586(+) (letA) [Escherichia coli strain 131]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCTGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACAGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378