Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   KIP81_RS08875 Genome accession   NZ_CP075172
Coordinates   1784197..1784943 (+) Length   248 a.a.
NCBI ID   WP_243602843.1    Uniprot ID   -
Organism   Streptococcus equinus strain SheepZ001     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1779197..1789943
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KIP81_RS08845 (KIP81_08835) comE/comE1 1779858..1780589 (-) 732 WP_243602842.1 response regulator transcription factor Regulator
  KIP81_RS08850 (KIP81_08840) - 1781545..1781853 (-) 309 WP_074567284.1 bacteriocin immunity protein -
  KIP81_RS08855 (KIP81_08845) - 1781853..1782104 (-) 252 Protein_1682 garvicin Q family class II bacteriocin -
  KIP81_RS08860 (KIP81_08850) - 1782410..1782583 (+) 174 WP_142349959.1 bacteriocin -
  KIP81_RS08865 (KIP81_08855) - 1782663..1783853 (+) 1191 WP_074630219.1 glycosyltransferase -
  KIP81_RS08870 (KIP81_08860) - 1783870..1784067 (+) 198 WP_074567282.1 bacteriocin -
  KIP81_RS08875 (KIP81_08865) comE/comE1 1784197..1784943 (+) 747 WP_243602843.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  KIP81_RS08880 (KIP81_08870) comA/nlmT 1785063..1787210 (+) 2148 WP_243602844.1 peptide cleavage/export ABC transporter Regulator
  KIP81_RS08885 (KIP81_08875) - 1787220..1788599 (+) 1380 WP_243602845.1 bacteriocin secretion accessory protein -
  KIP81_RS08890 (KIP81_08880) - 1789075..1789749 (-) 675 WP_243602846.1 type II CAAX endopeptidase family protein -

Sequence

Protein


Download         Length: 248 a.a.        Molecular weight: 29241.94 Da        Isoelectric Point: 7.7430

>NTDB_id=568272 KIP81_RS08875 WP_243602843.1 1784197..1784943(+) (comE/comE1) [Streptococcus equinus strain SheepZ001]
MIDIYILENNIFQQFQIEGIINTIMLKQHWNYRKLESFSTPRELTKKVFEKTCTQIFFLDLESVIDVESGINVAKYIREK
DLTAIIVFLSSHPELMLITYQSLVGAIDFIDKNLNNRVLNQRIEKCLNFAVAHSEKIDKENIFFYETSYSHVHVAFDDIL
YFETSPKSHCVILHMKDGELEFYGTIADIANTDRRLFKCHRSFVINLNNVIKFVKSKRIVFFKNGQYCQVARSKVITLLE
ILKFSREW

Nucleotide


Download         Length: 747 bp        

>NTDB_id=568272 KIP81_RS08875 WP_243602843.1 1784197..1784943(+) (comE/comE1) [Streptococcus equinus strain SheepZ001]
ATGATAGATATTTATATACTTGAAAATAACATTTTTCAGCAATTTCAGATTGAGGGTATCATTAATACTATTATGCTAAA
GCAGCATTGGAACTACAGAAAACTTGAATCTTTTAGTACACCTAGAGAGCTCACTAAAAAAGTTTTTGAAAAAACATGTA
CCCAAATCTTTTTTTTGGATTTAGAATCTGTAATTGATGTAGAGAGTGGAATAAATGTTGCAAAATACATTCGTGAAAAA
GATTTAACTGCAATTATTGTTTTTTTAAGTTCTCATCCTGAACTTATGTTAATAACTTACCAGTCCTTGGTTGGTGCAAT
TGATTTTATTGATAAAAATCTAAATAACCGTGTGTTAAACCAGCGTATTGAGAAATGTCTTAATTTTGCGGTAGCTCACT
CAGAAAAAATTGATAAGGAAAATATCTTTTTCTACGAAACCTCTTATTCACACGTCCATGTTGCATTTGACGATATTTTA
TATTTTGAGACCTCTCCAAAATCACATTGCGTAATCTTACACATGAAAGATGGAGAACTTGAGTTCTATGGAACTATTGC
TGATATTGCAAATACTGATAGACGATTATTCAAATGTCATCGCTCTTTTGTGATTAATCTTAACAATGTCATAAAATTTG
TAAAGAGTAAACGAATAGTATTTTTTAAAAATGGACAATACTGCCAAGTTGCTAGAAGTAAAGTCATAACCTTATTAGAA
ATTTTAAAATTCAGTCGTGAATGGTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-242)

Response regulator receiver domain (Response_reg)

(25-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

55.144

97.984

0.54
  comE/comE2 Streptococcus equinus JB1

41.423

96.371

0.399
  comE/blpR Streptococcus mutans UA159

39.271

99.597

0.391