Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MK801_RS08935 Genome accession   NZ_CP092748
Coordinates   1789321..1791399 (-) Length   692 a.a.
NCBI ID   WP_023189444.1    Uniprot ID   -
Organism   Lactococcus lactis strain 17M1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1784321..1796399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MK801_RS08915 (MK801_08910) fabI 1785632..1786384 (-) 753 WP_012897290.1 enoyl-ACP reductase FabI -
  MK801_RS08920 (MK801_08915) fabZ 1786660..1787115 (+) 456 WP_003130498.1 3-hydroxyacyl-ACP dehydratase FabZ -
  MK801_RS08925 (MK801_08920) - 1787183..1788301 (-) 1119 WP_254255505.1 M20 family metallopeptidase -
  MK801_RS08930 (MK801_08925) - 1788316..1789125 (-) 810 WP_081037457.1 ABC transporter substrate-binding protein -
  MK801_RS08935 (MK801_08930) uvrB 1789321..1791399 (-) 2079 WP_023189444.1 excinuclease ABC subunit UvrB Machinery gene
  MK801_RS08940 (MK801_08935) - 1791410..1791871 (-) 462 WP_306171264.1 RNA pyrophosphohydrolase -
  MK801_RS08945 (MK801_08940) def 1792019..1792654 (+) 636 WP_003130816.1 peptide deformylase -
  MK801_RS08950 (MK801_08945) gap 1792797..1793810 (-) 1014 WP_003130818.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  MK801_RS08955 (MK801_08950) - 1793983..1794453 (+) 471 WP_003130820.1 Rrf2 family transcriptional regulator -

Sequence

Protein


Download         Length: 692 a.a.        Molecular weight: 79103.41 Da        Isoelectric Point: 4.5652

>NTDB_id=568059 MK801_RS08935 WP_023189444.1 1789321..1791399(-) (uvrB) [Lactococcus lactis strain 17M1]
MAIERITDNKFELVSKYEPAGDQGEAIAELVDNIENGEKAQILRGATGTGKTYTMSQVIARTGKPTLVMAHNKTLAGQLY
SEFKEFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEY
QDSVVSLRPGQEISRDQLLNDLVGIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRIREIEVLTGQV
LGEVDHLAIFPATHFMTNDDRMEESIAKIEAELEEQLKVFRSEGKLLEAQRLEQRTNYDIEMLREMGYCNGVENYSRHMD
GREEGEPPYTLLDFFPDDFMIMIDESHMTMGQVKGMYNGDRARKEMLCNYGFRLPSALDNRPLKREEFESHVHQIVYVSA
TPGDYEMEQTDTIVEQIIRPTGLLDPVVEVRPMMGQIDDLVGEIHKRAEKNERVFVTTLTKKMSEDLTAYFKEMGIKVKY
MHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVILYSD
MAKALDENDPADKEILDSGYYTEYEGQKYKITRSMKHAMDETARRREIQMAYNEEHGITPQTIKKEIRDLIAITKKTDSG
EIEEVDASAMTKKERKALVKKLEKEMQQAASALDFEGAAQLRDMVLELRAMD

Nucleotide


Download         Length: 2079 bp        

>NTDB_id=568059 MK801_RS08935 WP_023189444.1 1789321..1791399(-) (uvrB) [Lactococcus lactis strain 17M1]
ATGGCTATAGAAAGAATAACAGATAATAAATTTGAACTTGTTTCAAAATATGAGCCAGCCGGTGACCAAGGTGAGGCGAT
TGCTGAGTTAGTAGATAATATTGAGAATGGGGAAAAAGCTCAAATTTTACGTGGAGCAACAGGAACAGGGAAAACTTACA
CCATGAGTCAAGTGATTGCACGGACAGGTAAACCTACTCTTGTTATGGCTCATAATAAAACACTGGCTGGTCAATTATAC
AGTGAATTTAAAGAATTTTTTCCAAATAATGCAGTCGAGTATTTCGTATCCTACTATGATTATTATCAACCCGAAGCCTA
TGTTCCAAGTTCTGACACCTATATTGAAAAAGACAGTTCGGTCAATGATGAAATTGACAAATTGCGTCACAGTGCGACCT
CAAGCTTATTGGAACGTAATGATGTGATTGTTGTGGCCTCAGTTTCTTGTATTTATGGTTTGGGTTCACCCAAAGAGTAT
CAAGATTCGGTGGTTTCATTGCGCCCAGGTCAAGAAATTTCTCGTGACCAACTTTTAAATGATTTGGTAGGAATTCAATT
TGAGCGAAATGATATTGACTTTCAACGGGGCTGTTTCCGAGTTCGCGGGGATGTTGTAGAAGTTTTTCCAGCCTCTCGTG
ATGAGCATGCCTTTCGTGTTGAATTTTTCGGTGATGAAATTGACCGTATCCGTGAAATTGAAGTTTTGACCGGACAAGTT
TTAGGTGAAGTAGACCATTTGGCAATTTTCCCAGCGACACATTTCATGACAAATGATGACCGTATGGAAGAATCAATTGC
CAAGATAGAAGCAGAATTAGAAGAACAATTAAAAGTTTTCCGCTCAGAAGGAAAACTTCTTGAGGCTCAACGTTTAGAAC
AAAGAACCAACTACGATATCGAAATGCTCCGTGAAATGGGTTATTGTAATGGGGTCGAAAACTATTCACGTCATATGGAC
GGGCGTGAGGAAGGCGAACCTCCGTATACTTTGCTTGATTTCTTTCCTGATGATTTCATGATTATGATTGATGAATCACA
CATGACCATGGGGCAAGTAAAAGGAATGTATAATGGTGACAGAGCCCGTAAAGAAATGCTTTGTAATTATGGATTCCGCC
TGCCTTCAGCCCTCGATAACCGTCCTTTAAAAAGAGAAGAATTTGAAAGTCATGTGCATCAAATTGTTTATGTTTCAGCA
ACCCCTGGGGATTATGAGATGGAGCAGACCGATACCATTGTTGAACAAATTATTCGTCCAACAGGTCTATTAGATCCTGT
CGTAGAAGTTCGACCAATGATGGGACAAATCGATGATTTAGTTGGTGAAATTCATAAACGAGCTGAGAAAAATGAACGAG
TATTCGTCACGACTTTGACTAAAAAGATGTCAGAAGATTTAACTGCCTATTTTAAGGAAATGGGGATAAAAGTTAAATAT
ATGCACTCGGATATCAAAACATTAGAACGAACCGAAATTATTCGGGATTTGCGTTTAGGAGTCTTTGATGTTCTGGTGGG
AATTAATTTGCTGCGTGAAGGGATAGATGTGCCAGAAGTTTCTTTAGTGGCGATTTTGGATGCTGATAAAGAAGGATTTT
TACGTAATGAACGTGGTTTGATTCAGACCATCGGTCGTGCGGCACGTAATAGTGAAGGGCACGTTATTCTTTATTCTGAT
ATGGCTAAAGCCCTTGATGAAAATGATCCTGCGGATAAAGAAATCTTAGATAGTGGTTATTATACAGAATACGAGGGTCA
AAAGTATAAAATAACGCGTTCAATGAAACATGCGATGGATGAAACAGCCCGTCGGCGTGAAATTCAAATGGCTTATAATG
AAGAACATGGAATCACACCTCAAACGATCAAAAAAGAAATTCGTGATTTGATTGCCATTACTAAGAAAACTGATTCTGGT
GAGATTGAAGAAGTTGATGCAAGTGCGATGACTAAGAAAGAACGTAAAGCATTAGTCAAAAAACTTGAAAAAGAAATGCA
ACAAGCGGCTAGCGCCCTCGACTTTGAAGGAGCTGCTCAGTTACGTGATATGGTATTAGAATTACGTGCAATGGATTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(165-255)

Helicase conserved C-terminal domain (Helicase_C)

(441-550)

Type III restriction enzyme, res subunit (ResIII)

(19-144)

Ultra-violet resistance protein B (UvrB)

(590-628)

UvrB/uvrC motif (UVR)

(657-690)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

82.029

99.711

0.818
  uvrB Streptococcus pneumoniae D39

82.029

99.711

0.818
  uvrB Streptococcus pneumoniae TIGR4

81.884

99.711

0.816