Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   MK801_RS00255 Genome accession   NZ_CP092748
Coordinates   49386..51356 (+) Length   656 a.a.
NCBI ID   WP_057720779.1    Uniprot ID   -
Organism   Lactococcus lactis strain 17M1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 44386..56356
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MK801_RS00235 (MK801_00235) - 44744..45052 (+) 309 WP_057720758.1 helix-turn-helix domain-containing protein -
  MK801_RS00240 (MK801_00240) - 45420..45767 (+) 348 WP_015427220.1 RicAFT regulatory complex protein RicA family protein -
  MK801_RS00245 (MK801_00245) hexA 45961..48483 (+) 2523 WP_254255580.1 DNA mismatch repair protein MutS Machinery gene
  MK801_RS00250 (MK801_00250) - 48598..49257 (+) 660 WP_254255581.1 hypothetical protein -
  MK801_RS00255 (MK801_00255) hexB 49386..51356 (+) 1971 WP_057720779.1 DNA mismatch repair endonuclease MutL Machinery gene
  MK801_RS00260 (MK801_00260) ruvA 51469..52062 (+) 594 WP_003131995.1 Holliday junction branch migration protein RuvA Machinery gene
  MK801_RS00265 (MK801_00265) ruvB 52189..53190 (+) 1002 WP_057720756.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  MK801_RS00270 (MK801_00270) - 53326..54210 (+) 885 WP_057720755.1 XRE/MutR family transcriptional regulator -
  MK801_RS00275 (MK801_00275) - 54430..54999 (+) 570 WP_012898697.1 hypothetical protein -

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 73780.02 Da        Isoelectric Point: 5.1824

>NTDB_id=567995 MK801_RS00255 WP_057720779.1 49386..51356(+) (hexB) [Lactococcus lactis strain 17M1]
MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKIIINVEEAGLRLIEVIDNGLGLEKEDVALALRRHATSK
IKDSADLFRIRTLGFRGEALPSIASVSQMTIETSTAEEESGTKLIAKGGNIETLEPLAKRVGTKISVANLFYNTPARLKY
IKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMRQIKGSDLDFELTGYVSIP
ELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFAILSIKIDPTLADVNVHPTKQEVRLSKERELMALISK
AIDEALSEGVLIPEALENLQGRAKEKESLSVQTELPLQNNPLYYDNVRQDFYVREEATFKINKNQASNDSSEQTFDNFTE
NQLNTDAVSEKMTDRTVESTTEITDNSLENTVSNFEIDFDNEVKISQSSTFPQLEYLAQLHATYLLCQSKEGLYLVDQHA
AQERIKYEYWKDKIGEVSMEQQILLAPYLFTLPKNDFIVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSI
NEMIDIILSSKEFSLKKYRHDLAAMVACKSSIKANHPLDAESARALLAELATCKNPYSCAHGRPTIVHFSGDDIQKMFRR
IQETHRSKAASWKDFE

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=567995 MK801_RS00255 WP_057720779.1 49386..51356(+) (hexB) [Lactococcus lactis strain 17M1]
GTGGGAAAAATTATTGAACTAAATGAAGCGCTCGCCAATCAAATTGCTGCTGGAGAGGTGGTTGAGCGGCCTGCTAGTGT
TGTCAAAGAATTAGTCGAAAACTCAATTGATGCTGGAAGCAGTAAAATTATTATCAATGTTGAAGAAGCTGGTTTGCGAT
TAATTGAAGTTATTGATAATGGTTTGGGTTTGGAAAAAGAAGATGTGGCTTTGGCTTTACGTCGTCATGCAACAAGTAAA
ATCAAGGATTCGGCAGATTTGTTTCGGATTAGAACACTCGGTTTTCGGGGGGAGGCTCTGCCATCAATCGCTTCTGTCAG
CCAGATGACCATTGAAACAAGTACGGCTGAGGAAGAATCAGGAACAAAACTAATTGCTAAAGGTGGAAATATCGAAACTT
TAGAACCACTTGCTAAGCGAGTGGGGACGAAAATTTCTGTTGCTAATCTTTTTTATAATACACCAGCAAGACTCAAGTAT
ATCAAGTCCTTGCAGGCTGAACTTTCTCATATCACAGACATCATCAACCGATTGAGTCTGGCTCATCCAGAGATTTCCTT
TACTTTAGTTAATGAGGGTAAAGAATTTTTGAAAACGGCTGGAAATGGTGATTTACGTCAGGTTATTGCTGCAATTTATG
GCATAGGGACAGCGAAAAAAATGCGTCAAATCAAGGGCTCAGACTTAGATTTTGAACTAACAGGTTATGTCAGCATACCA
GAGCTGACAAGGGCTAATCGTAATTATATTACGATTTTAATAAATGGTCGATTTATCAAAAACTTTTTATTGAATCGGGC
AATTTTAGAAGGATATGGCAATCGATTGATGGTGGGACGGTTCCCTTTTGCTATTTTATCGATTAAAATTGACCCAACAC
TTGCTGATGTTAATGTTCATCCGACAAAACAAGAGGTGCGTTTGTCTAAAGAGCGTGAATTGATGGCTTTAATTTCTAAA
GCAATTGATGAGGCTTTATCAGAAGGTGTTTTGATTCCAGAAGCTTTGGAAAATTTGCAAGGAAGAGCTAAAGAAAAGGA
GAGTCTTTCTGTTCAAACGGAACTTCCTTTGCAAAATAATCCTTTATATTATGATAATGTTCGCCAAGATTTTTATGTCA
GAGAAGAGGCAACTTTTAAAATCAATAAAAATCAAGCTTCAAATGATTCGTCTGAACAAACTTTTGATAATTTTACAGAA
AATCAACTTAATACAGATGCTGTCAGTGAAAAAATGACTGACAGAACTGTTGAAAGTACTACTGAAATTACTGACAACAG
TCTAGAAAATACTGTCAGCAACTTTGAAATTGATTTTGATAATGAAGTAAAGATAAGTCAGTCATCAACTTTTCCGCAGC
TTGAATACTTGGCACAATTGCATGCGACTTATTTACTTTGTCAGTCCAAAGAAGGACTTTATTTGGTTGACCAACATGCG
GCTCAAGAGCGAATCAAATATGAGTATTGGAAAGATAAAATTGGTGAGGTCAGTATGGAGCAACAAATTTTACTTGCACC
ATATTTGTTCACTTTACCCAAAAATGATTTTATTGTTTTAGCCGAGAAGAAAGATTTGTTGCATGAAGCCGGTGTTTTCT
TAGAAGAATACGGAGAAAATCAATTCATTTTAAGAGAACATCCAATCTGGTTAAAAGAAACCGAGATAGAGAAATCAATT
AATGAAATGATTGATATTATTCTCTCATCAAAAGAATTTTCACTCAAAAAATATCGTCATGATTTAGCTGCAATGGTTGC
TTGCAAAAGTTCAATTAAAGCTAATCATCCCCTTGATGCCGAATCAGCTAGAGCTTTACTCGCAGAATTAGCAACTTGTA
AAAATCCTTATAGTTGTGCGCATGGACGGCCAACGATTGTTCATTTTTCAGGGGATGACATTCAAAAAATGTTCCGGAGA
ATCCAAGAAACGCATCGTTCAAAAGCAGCTTCGTGGAAAGATTTTGAGTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(455-598)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

56.989

99.238

0.566