Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MJ614_RS13950 Genome accession   NZ_CP092647
Coordinates   2412996..2413586 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain EC5502     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2407996..2418586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MJ614_RS13935 uhpT 2408636..2410027 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  MJ614_RS13940 uhpC 2410165..2411484 (-) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  MJ614_RS13945 uhpB 2411494..2412996 (-) 1503 WP_001330988.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  MJ614_RS13950 letA 2412996..2413586 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  MJ614_RS13955 ilvN 2413661..2413951 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  MJ614_RS13960 ilvB 2413955..2415643 (-) 1689 WP_000168432.1 acetolactate synthase large subunit -
  MJ614_RS13965 ivbL 2415749..2415847 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  MJ614_RS13970 tisB 2416411..2416500 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  MJ614_RS13975 ysdE 2416763..2416837 (-) 75 WP_211180519.1 protein YsdE -
  MJ614_RS13980 emrD 2416919..2418103 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=567705 MJ614_RS13950 WP_000633668.1 2412996..2413586(-) (letA) [Escherichia coli strain EC5502]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=567705 MJ614_RS13950 WP_000633668.1 2412996..2413586(-) (letA) [Escherichia coli strain EC5502]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378