Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   MJ392_RS03440 Genome accession   NZ_CP092639
Coordinates   695583..696242 (-) Length   219 a.a.
NCBI ID   WP_001221492.1    Uniprot ID   -
Organism   Escherichia coli strain HS     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 690583..701242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MJ392_RS03415 (MJ392_03415) parE 690674..692566 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  MJ392_RS03420 (MJ392_03420) ygiN 692614..692928 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  MJ392_RS03425 (MJ392_03425) mdaB 692959..693540 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  MJ392_RS03430 (MJ392_03430) ygiZ 693859..694191 (+) 333 WP_000917684.1 DUF2645 family protein -
  MJ392_RS03435 (MJ392_03435) qseC 694237..695586 (-) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  MJ392_RS03440 (MJ392_03440) ciaR 695583..696242 (-) 660 WP_001221492.1 quorum sensing response regulator transcription factor QseB Regulator
  MJ392_RS03445 (MJ392_03445) ygiW 696394..696786 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  MJ392_RS03450 (MJ392_03450) ygiV 696839..697321 (+) 483 WP_000183505.1 GyrI-like domain-containing protein -
  MJ392_RS03455 (MJ392_03455) mqsR 697526..697822 (+) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  MJ392_RS03460 (MJ392_03460) mqsA 697824..698219 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  MJ392_RS03465 (MJ392_03465) ygiS 698352..699959 (+) 1608 WP_001295629.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24673.60 Da        Isoelectric Point: 6.9848

>NTDB_id=567545 MJ392_RS03440 WP_001221492.1 695583..696242(-) (ciaR) [Escherichia coli strain HS]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGDPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=567545 MJ392_RS03440 WP_001221492.1 695583..696242(-) (ciaR) [Escherichia coli strain HS]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGACCCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365