Detailed information NTG0056584

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: BSU6051_RS13280
• Genome accession: NC_020507
• Coordinates: 2640496..2641113 (-)
• Length: 205 a.a.
• NCBI ID: WP_004398514.1
• Uniprot ID: A0AAE2SLR2
• Organism: Bacillus subtilis subsp. subtilis 6051-HGW
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2635496..2646113

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSU6051_RS13255 (BSU6051_25550)	rpsT	2635798..2636064 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
BSU6051_RS13260 (BSU6051_25560)	holA	2636079..2637122 (-)	1044	WP_003229987.1	DNA polymerase III subunit delta	-
BSU6051_RS22525	-	2637162..2637311 (-)	150	WP_003229985.1	hypothetical protein	-
BSU6051_RS21915 (BSU6051_25569)	yqzM	2637352..2637486 (+)	135	WP_003229983.1	YqzM family protein	-
BSU6051_RS13270 (BSU6051_25570)	comEC	2637526..2639856 (-)	2331	WP_009967776.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BSU6051_RS13275 (BSU6051_25580)	comEB	2639860..2640429 (-)	570	WP_003229978.1	ComE operon protein 2	-
BSU6051_RS13280 (BSU6051_25590)	comEA	2640496..2641113 (-)	618	WP_004398514.1	competence protein ComEA	Machinery gene
BSU6051_RS13285 (BSU6051_25600)	comER	2641197..2642018 (+)	822	WP_004398597.1	late competence protein ComER	-
BSU6051_RS13290 (BSU6051_25610)	yqeM	2642084..2642827 (-)	744	WP_003229973.1	class I SAM-dependent methyltransferase	-
BSU6051_RS13295 (BSU6051_25620)	rsfS	2642824..2643180 (-)	357	WP_003229971.1	ribosome silencing factor	-
BSU6051_RS13300 (BSU6051_25630)	yqeK	2643198..2643758 (-)	561	WP_004399059.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
BSU6051_RS13305 (BSU6051_25640)	nadD	2643748..2644317 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
BSU6051_RS13310 (BSU6051_25650)	yhbY	2644329..2644619 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-
BSU6051_RS13315 (BSU6051_25660)	aroE	2644613..2645455 (-)	843	WP_003229967.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 205 a.a.
• Molecular weight: 21769.45 Da
• Isoelectric Point: 4.7220

>NTDB_id=56584 BSU6051_RS13280 WP_004398514.1 2640496..2641113(-) (comEA) [Bacillus subtilis subsp. subtilis 6051-HGW]
MNWLNQHKKAIILAASAAVFTAIMIFLATGKNKEPVKQAVPTETENTVVKQEANNDESNETIVIDIKGAVQHPGVYEMRT
GDRVSQAIEKAGGTSEQADEAQVNLAEILQDGTVVYIPKKGEETAVQQGGGGSVQSDGGKGALVNINTATLEELQGISGV
GPSKAEAIIAYREENGRFQTIEDITKVSGIGEKSFEKIKSSITVK

Nucleotide

• Length: 618 bp

>NTDB_id=56584 BSU6051_RS13280 WP_004398514.1 2640496..2641113(-) (comEA) [Bacillus subtilis subsp. subtilis 6051-HGW]
ATGAATTGGTTGAATCAGCATAAGAAAGCAATTATTTTAGCGGCTTCTGCGGCTGTTTTCACAGCGATTATGATCTTTCT
GGCCACAGGGAAAAATAAAGAGCCGGTGAAGCAAGCTGTACCAACAGAGACAGAAAATACAGTGGTAAAGCAGGAAGCAA
ACAACGACGAGTCAAACGAAACAATTGTGATAGACATCAAAGGTGCTGTTCAGCATCCTGGCGTTTATGAAATGCGAACA
GGGGACAGAGTATCTCAGGCAATTGAGAAAGCGGGCGGGACCAGTGAACAAGCAGACGAAGCGCAAGTAAATTTGGCGGA
GATTCTGCAGGACGGGACAGTGGTGTACATCCCGAAAAAGGGAGAGGAAACAGCAGTGCAGCAAGGTGGCGGAGGGTCTG
TCCAAAGCGATGGAGGGAAGGGAGCGCTGGTGAATATCAATACAGCAACCTTAGAGGAGTTACAAGGCATCTCAGGGGTG
GGGCCATCCAAAGCTGAAGCTATTATTGCATACCGGGAGGAAAACGGTCGTTTCCAAACAATTGAAGATATCACTAAGGT
TTCAGGAATAGGTGAAAAGTCATTTGAGAAAATAAAGTCTTCCATTACAGTAAAGTGA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (142-203)

• SLBB domain (SLBB) (63-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	100	100	1
comEA	Staphylococcus aureus MW2	37.273	100	0.4
comEA	Staphylococcus aureus N315	36.364	100	0.39