Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Regulator
Locus tag   SITYG_RS10230 Genome accession   NZ_AP014880
Coordinates   2003736..2003882 (-) Length   48 a.a.
NCBI ID   WP_003075491.1    Uniprot ID   O33651
Organism   Streptococcus intermedius strain TYG1620     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1998736..2008882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS10205 (SITYG_20140) - 1998745..2001321 (+) 2577 WP_096363304.1 YfhO family protein -
  SITYG_RS10220 (SITYG_20150) comE 2001645..2002394 (-) 750 WP_096363305.1 competence system response regulator transcription factor ComE Regulator
  SITYG_RS10225 (SITYG_20160) comD/comD1 2002394..2003719 (-) 1326 WP_221761483.1 GHKL domain-containing protein Regulator
  SITYG_RS10230 (SITYG_20170) comC 2003736..2003882 (-) 147 WP_003075491.1 bacteriocin Regulator
  SITYG_RS10240 (SITYG_20180) rlmH 2004159..2004638 (-) 480 WP_096363307.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SITYG_RS10245 (SITYG_20190) htrA 2004842..2006032 (+) 1191 WP_020999302.1 S1C family serine protease Regulator
  SITYG_RS10250 (SITYG_20200) spo0J 2006087..2006854 (+) 768 WP_096363308.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 48 a.a.        Molecular weight: 5605.69 Da        Isoelectric Point: 10.5532

>NTDB_id=56585 SITYG_RS10230 WP_003075491.1 2003736..2003882(-) (comC) [Streptococcus intermedius strain TYG1620]
MKKLFAKKEVVKKEVVKFKELNDEQLDKVIGGDSRIRMGFDFSKLFGK

Nucleotide


Download         Length: 147 bp        

>NTDB_id=56585 SITYG_RS10230 WP_003075491.1 2003736..2003882(-) (comC) [Streptococcus intermedius strain TYG1620]
ATGAAAAAGTTGTTTGCTAAAAAAGAGGTAGTAAAAAAGGAAGTTGTAAAATTTAAAGAGTTAAATGATGAACAGTTAGA
TAAAGTCATTGGTGGGGATAGTCGAATCAGAATGGGATTTGATTTTTCTAAACTTTTTGGTAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O33651

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus sinensis strain Forsyth1A

54.054

77.083

0.417

Multiple sequence alignment