Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   LU695_RS03235 Genome accession   NZ_CP092500
Coordinates   660705..661364 (-) Length   219 a.a.
NCBI ID   WP_258314108.1    Uniprot ID   -
Organism   Escherichia coli strain A30     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 655705..666364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LU695_RS03205 (LU695_03205) ygiN 656606..656920 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  LU695_RS03210 (LU695_03210) mdaB 656951..657532 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  LU695_RS03215 (LU695_03215) - 657782..658261 (+) 480 WP_000065332.1 Hcp family type VI secretion system effector -
  LU695_RS03220 (LU695_03220) - 658264..658974 (+) 711 WP_000834029.1 hypothetical protein -
  LU695_RS03225 (LU695_03225) ygiZ 658981..659313 (+) 333 WP_000914691.1 DUF2645 family protein -
  LU695_RS03230 (LU695_03230) qseC 659359..660708 (-) 1350 WP_000673355.1 quorum sensing histidine kinase QseC -
  LU695_RS03235 (LU695_03235) ciaR 660705..661364 (-) 660 WP_258314108.1 quorum sensing response regulator transcription factor QseB Regulator
  LU695_RS03240 (LU695_03240) ygiW 661516..661908 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  LU695_RS03245 (LU695_03245) ygiV 661961..662443 (+) 483 WP_000183494.1 AraC family transcriptional regulator -
  LU695_RS03250 (LU695_03250) parC 662989..665247 (+) 2259 WP_001281881.1 DNA topoisomerase IV subunit A -
  LU695_RS03255 (LU695_03255) plsC 665480..666217 (+) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24744.72 Da        Isoelectric Point: 7.4216

>NTDB_id=565518 LU695_RS03235 WP_258314108.1 660705..661364(-) (ciaR) [Escherichia coli strain A30]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEKRVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=565518 LU695_RS03235 WP_258314108.1 660705..661364(-) (ciaR) [Escherichia coli strain A30]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGAAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365