Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   MJJ13_RS03620 Genome accession   NZ_CP092449
Coordinates   727436..728095 (-) Length   219 a.a.
NCBI ID   WP_239812931.1    Uniprot ID   -
Organism   Escherichia coli isolate TKEC21-17     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 722436..733095
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MJJ13_RS03590 (MJJ13_03580) ygiN 723691..724005 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  MJJ13_RS03595 (MJJ13_03585) mdaB 724036..724617 (-) 582 WP_032247753.1 NADPH:quinone oxidoreductase MdaB -
  MJJ13_RS03600 (MJJ13_03590) - 724936..725016 (+) 81 Protein_706 DUF2645 domain-containing protein -
  MJJ13_RS03610 (MJJ13_03600) - 725787..726044 (+) 258 Protein_708 DUF2645 family protein -
  MJJ13_RS03615 (MJJ13_03605) qseC 726090..727439 (-) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  MJJ13_RS03620 (MJJ13_03610) ciaR 727436..728095 (-) 660 WP_239812931.1 quorum sensing response regulator transcription factor QseB Regulator
  MJJ13_RS03625 (MJJ13_03615) ygiW 728247..728639 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  MJJ13_RS03630 (MJJ13_03620) ygiV 728692..729174 (+) 483 WP_000183505.1 GyrI-like domain-containing protein -
  MJJ13_RS03635 (MJJ13_03625) mqsR 729379..729675 (+) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  MJJ13_RS03640 (MJJ13_03630) mqsA 729677..730072 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  MJJ13_RS03645 (MJJ13_03635) ygiS 730205..731812 (+) 1608 WP_001295629.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24657.60 Da        Isoelectric Point: 6.9850

>NTDB_id=565195 MJJ13_RS03620 WP_239812931.1 727436..728095(-) (ciaR) [Escherichia coli isolate TKEC21-17]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQAGNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=565195 MJJ13_RS03620 WP_239812931.1 727436..728095(-) (ciaR) [Escherichia coli isolate TKEC21-17]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCGGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365