Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   AH5611_RS05175 Genome accession   NZ_CP092055
Coordinates   1074198..1075979 (+) Length   593 a.a.
NCBI ID   WP_164046323.1    Uniprot ID   -
Organism   Staphylococcus aureus strain USA600     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1069198..1080979
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AH5611_RS05155 (AH5611_000993) polX 1069316..1071028 (+) 1713 WP_000161953.1 DNA polymerase/3'-5' exonuclease PolX -
  AH5611_RS05160 (AH5611_000994) mutS/mutS2 1071038..1073386 (+) 2349 WP_001249279.1 endonuclease MutS2 Machinery gene
  AH5611_RS05165 (AH5611_000995) trxA 1073559..1073873 (+) 315 WP_001018928.1 thioredoxin -
  AH5611_RS05170 - 1073936..1074007 (-) 72 WP_223200532.1 hypothetical protein -
  AH5611_RS05175 (AH5611_000996) uvrC 1074198..1075979 (+) 1782 WP_164046323.1 excinuclease ABC subunit UvrC Machinery gene
  AH5611_RS05180 (AH5611_000997) - 1076303..1076917 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  AH5611_RS05185 (AH5611_000998) sdhA 1076969..1078735 (+) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  AH5611_RS05190 (AH5611_000999) sdhB 1078735..1079550 (+) 816 WP_000132057.1 succinate dehydrogenase iron-sulfur subunit -
  AH5611_RS05195 (AH5611_001000) racE 1079790..1080590 (+) 801 WP_001039660.1 glutamate racemase -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68683.43 Da        Isoelectric Point: 9.7443

>NTDB_id=564798 AH5611_RS05175 WP_164046323.1 1074198..1075979(+) (uvrC) [Staphylococcus aureus strain USA600]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRHFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMMKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKEMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFIDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGSKRKTLLLRSF
GSIKKMKEATLEDFKNLGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=564798 AH5611_RS05175 WP_164046323.1 1074198..1075979(+) (uvrC) [Staphylococcus aureus strain USA600]
TTGGAAGATTATAAACAACGAATTAAAAATAAATTAAATGTTGTACCTATGGAACCGGGTTGCTATTTAATGAAAGACCG
CAATGATCAAGTGATATATGTTGGGAAAGCTAAAAAATTAAGAAATCGATTACGATCATATTTTACGGGCGCACACGATG
CTAAAACAACGAGACTTGTTGGAGAAATACGGCATTTTGAATTTATTGTCACATCTAGTGAAACAGAGTCATTATTACTT
GAATTAAATTTGATCAAACAATATCAACCTAGATACAACATTTTATTAAAAGATGATAAAAGTTATCCATTTATTAAAAT
AACAAAGGAAAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAT
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAATAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGCTGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAACGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTGCCGCGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGAGATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCAATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTATCGACGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGCCGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACCTTTCATAGACAAACACGTC
AAAAGACCGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAGCAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATTTAGGTATTCCTGAAAACGTTGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)

UvrB/uvrC motif (UVR)

(200-233)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae R6

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae D39

57.265

98.651

0.565