Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MCU78_RS25165 Genome accession   NZ_CP092051
Coordinates   5728971..5731103 (+) Length   710 a.a.
NCBI ID   WP_185943705.1    Uniprot ID   -
Organism   Streptomyces sp. TYQ1024     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 5723971..5736103
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MCU78_RS25140 (MCU78_25140) coaE 5724504..5725118 (+) 615 WP_185943700.1 dephospho-CoA kinase -
  MCU78_RS25145 (MCU78_25145) - 5725246..5725614 (+) 369 WP_185943701.1 tetratricopeptide repeat protein -
  MCU78_RS25150 (MCU78_25150) - 5725869..5726150 (-) 282 WP_185943702.1 DUF6343 family protein -
  MCU78_RS25155 (MCU78_25155) - 5726235..5727689 (-) 1455 WP_185943703.1 WGR domain-containing protein -
  MCU78_RS25160 (MCU78_25160) - 5727781..5728743 (-) 963 WP_185943704.1 glycerophosphodiester phosphodiesterase family protein -
  MCU78_RS25165 (MCU78_25165) uvrB 5728971..5731103 (+) 2133 WP_185943705.1 excinuclease ABC subunit UvrB Machinery gene
  MCU78_RS25170 (MCU78_25170) - 5731383..5731961 (+) 579 WP_185943706.1 TerD family protein -
  MCU78_RS25175 (MCU78_25175) - 5732084..5734018 (+) 1935 WP_185943707.1 TerD family protein -
  MCU78_RS25180 (MCU78_25180) - 5734203..5735201 (+) 999 WP_185943708.1 TerC family protein -

Sequence

Protein


Download         Length: 710 a.a.        Molecular weight: 79725.72 Da        Isoelectric Point: 4.8143

>NTDB_id=564668 MCU78_RS25165 WP_185943705.1 5728971..5731103(+) (uvrB) [Streptomyces sp. TYQ1024]
MRPVSQIERKVAPFEVVSPYQPSGDQPAAIAELEKRIRAGEKDVVLLGATGTGKSATTAWMIEKLQRPTLVMAPNKTLAA
QLANEFRELLPNNAVEYFVSYYDYYQPEAYVPQSDTYIEKDSSINEEVERLRHSATNSLLTRRDVVVVASVSCIYGLGTP
QEYVDRMVPLKVGEEIDRDDLLRRFVEIQYTRNDLAFTRGTFRVRGDTIEIFPVYEELAVRIEMFGDEIEALSTLHPLTG
EVISDDQELYVFPASHYVAGPERMEKAIAGIEAELEETLARMEKQGKLLEAQRLRMRTTYDIEMMRQIGSCSGIENYSLH
MDDREPGSPPNTLLDFFPDDFLLVIDESHVTVPQIGAMYEGDASRKRTLVEHGFRLPSAMDNRPLKWEEFTERIGQTVYL
SATPGKYELAKSDGYVEQIIRPTGLVDPEVVVKPTEGQIDDLVHEIRERTEKDERVLVTTLTKKMAEDLTDYFLELGIQV
RYLHSDVDTLRRVELLRELRAGEYDVLVGINLLREGLDLPEVSLVAILDADKEGFLRSGTSLIQTIGRAARNVSGQVHMY
ADKITPAMEKAIDETNRRRAKQIAYNKERGIDPQPLRKKIGDIVATIVREEIDTQELLGTGYRKPAEGKGGEKKGKAPVP
TAAGGGKKGKAKAAVATDRPAAELAQLIEDMTDRMRAAAAELQFEVAARLRDEVGELKKELRQMKEAGVA

Nucleotide


Download         Length: 2133 bp        

>NTDB_id=564668 MCU78_RS25165 WP_185943705.1 5728971..5731103(+) (uvrB) [Streptomyces sp. TYQ1024]
ATGCGGCCCGTTTCCCAGATCGAACGCAAAGTGGCGCCTTTCGAGGTCGTCAGTCCCTACCAGCCCAGCGGTGACCAGCC
GGCTGCCATCGCCGAGCTGGAGAAGCGCATCCGCGCGGGCGAGAAGGACGTCGTCCTGCTCGGCGCGACCGGTACCGGCA
AGTCGGCGACCACGGCGTGGATGATCGAGAAGCTCCAGCGGCCGACGCTCGTCATGGCGCCCAACAAGACGCTCGCGGCC
CAGCTCGCCAACGAGTTCCGCGAGCTCCTGCCCAACAACGCGGTCGAGTACTTCGTCTCGTACTACGACTACTACCAGCC
CGAGGCGTACGTCCCCCAGTCGGACACCTACATCGAGAAGGACTCCTCGATCAACGAGGAGGTGGAGCGGCTGCGGCACT
CCGCGACCAACTCGCTGCTCACCCGGCGGGACGTGGTCGTGGTGGCCTCGGTGTCCTGCATCTACGGCCTGGGCACGCCC
CAGGAGTACGTGGACCGCATGGTCCCGCTCAAGGTCGGTGAGGAGATCGACCGGGACGATCTGCTGCGCCGCTTCGTGGA
GATCCAGTACACGCGCAACGACCTGGCCTTCACCCGGGGCACCTTCCGGGTGCGCGGGGACACCATCGAGATCTTCCCGG
TCTACGAGGAACTGGCCGTCCGCATCGAGATGTTCGGCGACGAGATCGAGGCGCTGTCCACGCTGCACCCGCTGACCGGC
GAGGTCATCTCGGACGACCAGGAGCTGTACGTCTTCCCCGCCAGCCACTACGTCGCCGGCCCCGAGCGGATGGAGAAGGC
CATCGCCGGGATCGAGGCGGAGCTGGAGGAGACGCTGGCGCGGATGGAGAAGCAGGGCAAGCTGCTGGAGGCCCAGCGGC
TGCGCATGCGCACCACGTACGACATCGAGATGATGCGCCAGATCGGCTCCTGCTCCGGCATCGAGAACTACTCGCTGCAC
ATGGACGACCGCGAGCCCGGCTCCCCGCCCAACACCCTGCTGGACTTCTTCCCGGACGACTTCCTCCTCGTCATCGACGA
GTCGCACGTCACCGTGCCGCAGATCGGCGCCATGTACGAGGGCGACGCCTCCCGCAAGCGCACCCTGGTCGAGCACGGCT
TCCGGCTGCCGTCCGCCATGGACAACCGCCCGCTGAAGTGGGAGGAGTTCACCGAGCGCATCGGGCAGACCGTCTACCTG
TCGGCGACGCCCGGGAAGTACGAGCTGGCGAAGTCCGACGGCTACGTCGAGCAGATCATCCGGCCCACCGGGCTGGTCGA
CCCGGAGGTCGTCGTCAAGCCGACCGAGGGCCAGATCGACGACCTGGTGCACGAGATCCGCGAGCGCACCGAGAAGGACG
AGCGGGTCCTGGTCACCACGCTCACCAAGAAGATGGCCGAGGACCTGACGGACTACTTCCTGGAGCTTGGCATCCAGGTG
CGCTACCTGCACAGCGACGTCGACACCCTCCGCCGCGTCGAGCTGCTGCGCGAGCTGCGGGCCGGCGAGTACGACGTGCT
GGTGGGCATCAACCTGCTGCGCGAGGGCCTCGACCTGCCCGAGGTGTCGCTGGTGGCGATCCTCGACGCCGACAAGGAGG
GCTTCCTGCGCTCCGGCACCTCGCTGATCCAGACTATTGGCCGCGCGGCGCGCAACGTCTCCGGCCAGGTCCATATGTAC
GCCGACAAGATCACGCCGGCGATGGAGAAGGCCATCGACGAGACCAACCGGCGCCGCGCCAAACAGATCGCGTACAACAA
GGAGCGGGGCATCGACCCGCAGCCGCTGCGGAAGAAGATCGGTGACATCGTCGCCACCATCGTCCGCGAGGAGATCGACA
CCCAGGAGCTGCTGGGCACGGGCTACCGGAAGCCGGCGGAGGGCAAGGGCGGGGAGAAGAAGGGGAAGGCCCCCGTCCCG
ACGGCCGCGGGCGGCGGCAAGAAGGGCAAGGCGAAGGCGGCCGTCGCGACCGACCGGCCGGCGGCGGAACTCGCCCAGCT
CATCGAGGACATGACGGACCGCATGCGGGCCGCCGCGGCGGAGCTCCAGTTCGAGGTCGCCGCGCGGCTGCGCGACGAGG
TCGGCGAGCTGAAGAAGGAGCTGCGGCAGATGAAGGAGGCGGGGGTCGCCTGA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(441-551)

UvrB/uvrC motif (UVR)

(666-700)

Type III restriction enzyme, res subunit (ResIII)

(25-134)

Ultra-violet resistance protein B (UvrB)

(559-600)

UvrB interaction domain (UvrB_inter)

(169-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.726

96.62

0.558
  uvrB Streptococcus pneumoniae R6

57.726

96.62

0.558
  uvrB Streptococcus pneumoniae D39

57.726

96.62

0.558