Detailed information NTG0564476

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: KG086_RS10480
• Genome accession: NZ_CP074378
• Coordinates: 2230063..2232255 (-)
• Length: 730 a.a.
• NCBI ID: WP_129302255.1
• Uniprot ID: A0A4Q1TRY3
• Organism: Lacticaseibacillus chiayiensis strain FBL7
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2225063..2237255

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KG086_RS10460 (KG086_10460)	-	2225260..2225463 (+)	204	WP_129302258.1	hypothetical protein	-
KG086_RS10465 (KG086_10465)	-	2225924..2226898 (+)	975	Protein_2036	aldo/keto reductase	-
KG086_RS10470 (KG086_10470)	-	2227201..2228556 (-)	1356	WP_129302257.1	threonine/serine ThrE exporter family protein	-
KG086_RS10475 (KG086_10475)	-	2228671..2230050 (-)	1380	WP_129302256.1	bacteriocin secretion accessory protein	-
KG086_RS10480 (KG086_10480)	comA	2230063..2232255 (-)	2193	WP_129302255.1	peptide cleavage/export ABC transporter	Regulator
KG086_RS10485 (KG086_10485)	-	2232564..2232710 (-)	147	WP_158280525.1	bacteriocin-like peptide, LSEI_2386 family	-
KG086_RS10490 (KG086_10490)	-	2232879..2234180 (+)	1302	WP_213224079.1	GHKL domain-containing protein	-
KG086_RS10495 (KG086_10495)	-	2234182..2234988 (+)	807	WP_129302254.1	response regulator transcription factor	-
KG086_RS10500 (KG086_10500)	-	2235172..2235456 (-)	285	WP_129302253.1	hypothetical protein	-
KG086_RS10505 (KG086_10505)	-	2236395..2236601 (-)	207	WP_129302252.1	TmhB bacteriocin enhancer peptide	-
KG086_RS10510 (KG086_10510)	-	2236622..2236861 (-)	240	WP_129302251.1	Blp family class II bacteriocin	-
KG086_RS10515 (KG086_10515)	-	2236872..2237237 (-)	366	WP_158280576.1	thioredoxin family protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81833.32 Da
• Isoelectric Point: 7.6104

>NTDB_id=564476 KG086_RS10480 WP_129302255.1 2230063..2232255(-) (comA) [Lacticaseibacillus chiayiensis strain FBL7]
MFKYKFKLGQATYYKRHYTPQVDERDCGVAALNMLLKFHRSDYSLAHLRQLAKTDQEGTTALGIVRAAQELHFETKAVKA
DMTLFDLNDAPYPILVHVLKRGELLHYYVVFKATKDYILIGDPDPSVAMTWLSKDEFAKEWSGVAIFIAPEPQYQPRKED
KDSLFAFVPLLARQKVIIANIIVAALLLTVISIVGSYFLQSIIDTYIPSAMRTTLGMIASGLILAYILQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFATRRTGEIVSRFSDANKIIDALANTIMTLFLDVWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLSYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRHLTDRRLIDGAINVHDVSFKYGFGQDILKHVHLEVPANAKYTIVGMSGSGKSTLAKLLVGFYPIDTGKGKITFNGAQI
NDVALTTLRQYIEYVPQEPFIFSGSVMENLTLGSRADLTQAQLEDACAVAEIATDIMNLPQMWQTKLTESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERRIVDRLLAMEDRTIIFVAHRLTIAAKTEQIVVMNHGEIVEQGNHAELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=564476 KG086_RS10480 WP_129302255.1 2230063..2232255(-) (comA) [Lacticaseibacillus chiayiensis strain FBL7]
ATGTTCAAATACAAATTCAAACTAGGCCAAGCAACATACTACAAACGTCATTACACGCCTCAGGTGGATGAGCGTGATTG
CGGCGTTGCGGCGCTTAATATGTTACTGAAGTTTCATAGGTCCGACTATTCCCTTGCGCATTTACGGCAATTAGCCAAGA
CGGATCAGGAAGGAACAACAGCATTAGGCATTGTTCGGGCCGCCCAGGAACTTCATTTTGAAACCAAGGCAGTTAAGGCG
GATATGACGTTGTTTGATTTAAATGATGCGCCATATCCGATCTTGGTGCATGTTTTGAAGCGTGGCGAGTTGTTGCATTA
TTATGTCGTGTTTAAGGCGACGAAGGATTATATCTTAATCGGTGATCCTGACCCTTCAGTCGCAATGACCTGGCTTTCAA
AAGATGAGTTTGCCAAGGAGTGGTCGGGGGTGGCTATCTTTATTGCTCCTGAACCACAATATCAACCGCGCAAAGAGGAC
AAAGACAGCTTGTTTGCCTTCGTGCCGTTACTTGCGCGGCAAAAAGTGATCATTGCCAATATTATTGTTGCGGCTTTGTT
GCTCACGGTGATTAGTATTGTCGGGTCGTATTTTTTGCAATCGATTATTGATACCTATATTCCCAGTGCCATGCGGACAA
CCTTGGGCATGATCGCCAGTGGGCTGATTCTCGCTTACATTCTTCAATCTGTTTTGACGTATGGTCAGAACTTTTTGATG
GCGGTTTTAGGCCAGCGGTTGTCGATTGACGTTATTTTGGGTTACGTTCGGCATCTGTATGAATTACCCATGTCTTTTTT
TGCAACACGCCGGACAGGGGAGATTGTGTCGCGGTTTTCGGATGCCAATAAAATTATCGATGCCTTGGCGAATACGATCA
TGACCCTGTTTCTTGACGTTTGGATCGTGCTTATTTTAGGCATTGTTCTAGGCATTCAAAATACCACGTTGTTCCTGGTG
TCCTTAATTGCGGTGCCTTGTTACTTGGTGATTGTTTTCGCGTTTCAACGTCCTTTCAATCGGCTGAATCAAGAGACAAT
GGAAAGCAATGCCATTTTGAGTTCATCAATTATTGAGGATCTAAACGGTATTGAGACCATTAAGTCGCTGACAGGCGAAA
AAGTCAGTTATGAGCGGGTTGACCGTGAATTCGTCACGTATTTAAAAAAGTCATTCAATTACACGAAAGCCGACCAGCTT
CAACAAGCTATCAAAGGGTTGCTGAAACTCGTCTTGAATGTGGTGGTGTTGTGGATTGGGGCGAGTCTGGTGATGGCGAA
CAAGATGAGCTTGGGGCAGATGCTGACGTTCAATGCCTTGCTGTCATATTTCACCAATCCGTTAGAAAGTATCATTAACT
TGCAACCTAAATTACAAATGGCCAAGGTGGCGAATAATCGGCTGAATGAGGTTTATTTGGTTGAATCTGAGTTTAAAGAA
CAGCGCCATCTGACCGATCGCCGCCTGATCGATGGTGCCATCAACGTGCATGATGTTTCCTTTAAATACGGGTTTGGTCA
GGATATTTTGAAGCATGTCCATCTTGAAGTGCCCGCAAACGCTAAATACACGATTGTTGGGATGAGTGGGTCAGGCAAGT
CAACGTTGGCCAAATTATTAGTCGGCTTTTACCCGATCGATACAGGCAAGGGAAAAATCACCTTTAATGGCGCGCAGATT
AATGATGTGGCGCTCACGACGCTGCGGCAATATATCGAGTATGTGCCGCAAGAGCCGTTTATTTTTTCCGGATCGGTGAT
GGAAAACTTAACGTTAGGCAGTCGTGCCGATTTGACGCAGGCGCAACTTGAAGACGCATGTGCCGTTGCGGAGATTGCCA
CGGATATTATGAATTTGCCGCAAATGTGGCAGACCAAGCTCACGGAAAGCGGGAGCATTTTATCAGGCGGTCAGAAGCAG
CGCTTGGCGATTGCACGGGCGTTGTTATCGCCGGCCAAAGTGCTGATTTTTGATGAGTCGACTAGCAGTCTGGATACCAT
CACGGAGCGGCGGATTGTGGATCGGTTGTTGGCGATGGAAGATCGAACCATTATTTTTGTTGCCCATCGACTCACAATTG
CGGCCAAAACCGAACAGATTGTCGTCATGAATCATGGCGAAATTGTCGAGCAAGGCAATCACGCAGAACTGCTGGCCAAA
CAAGGCTATTATGCGCGGCTGGTGAGTGAATGA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (180-448)

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter (ABC_tran) (510-662)

3D structure

• AlphaFold DB: A0A4Q1TRY3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.322	97.945	0.571
comA	Streptococcus pneumoniae Rx1	58.322	97.945	0.571
comA	Streptococcus pneumoniae D39	58.322	97.945	0.571
comA	Streptococcus pneumoniae R6	58.322	97.945	0.571
comA	Streptococcus mitis SK321	58.182	97.945	0.57
comA	Streptococcus pneumoniae TIGR4	57.902	97.945	0.567
comA	Streptococcus gordonii str. Challis substr. CH1	56.485	98.219	0.555
comA/nlmT	Streptococcus mutans UA159	54.432	98.904	0.538