Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   MBG98_RS00380 Genome accession   NZ_CP092038
Coordinates   80123..82114 (+) Length   663 a.a.
NCBI ID   WP_010945833.1    Uniprot ID   Q5ZZD9
Organism   Legionella pneumophila strain 11052018-5     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 75123..87114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MBG98_RS00355 (MBG98_00355) - 75808..77112 (+) 1305 WP_015444960.1 ATP-grasp domain-containing protein -
  MBG98_RS00360 (MBG98_00360) - 77133..77723 (+) 591 WP_015444959.1 RBBP9/YdeN family alpha/beta hydrolase -
  MBG98_RS00365 (MBG98_00365) - 77707..78654 (+) 948 WP_010945830.1 DMT family transporter -
  MBG98_RS00375 (MBG98_00375) - 78898..80076 (-) 1179 WP_010945831.1 pyridoxal phosphate-dependent aminotransferase -
  MBG98_RS00380 (MBG98_00380) uvrB 80123..82114 (+) 1992 WP_010945833.1 excinuclease ABC subunit UvrB Machinery gene
  MBG98_RS00390 (MBG98_00390) - 82469..84070 (+) 1602 WP_010945834.1 putative bifunctional diguanylate cyclase/phosphodiesterase -
  MBG98_RS00395 (MBG98_00395) - 84162..85733 (-) 1572 WP_010945835.1 FMN-binding glutamate synthase family protein -
  MBG98_RS00400 (MBG98_00400) - 85811..86125 (-) 315 WP_010945836.1 cell division protein ZapA -
  MBG98_RS00405 (MBG98_00405) - 86281..86862 (+) 582 WP_010945837.1 UPF0149 family protein -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 75631.39 Da        Isoelectric Point: 5.1412

>NTDB_id=564447 MBG98_RS00380 WP_010945833.1 80123..82114(+) (uvrB) [Legionella pneumophila strain 11052018-5]
MKDLFKIYSNYQPAGDQPTAIASLIDGLESGLAKQTLLGVTGSGKTFTIAHVIQAMKRPTLIMAPNKTLAAQLYGEFKAF
FPDNAVEYFVSYYDYYQPEAYVPASDTFIEKDASINEHIEQMRLSATKALIERKDAIIVATVSAIYGLGDPDSYLRMLLH
LSRGEQSDQRKILKRLAEMQYTRTNLSLERGQFRVHGDVIDIFPADSEKEAIRIELFDDEVDNIARFDPLTGEILQRLPR
VTIFPKTHYVTPRERILETVEKVKVELQERLAELNAQNKLVEAQRLEQRTCFDIEMMLELGYCSGIENYSRYLSNREAGE
APPTLFDYLPPEALLIIDESHVTVPQIGGMYRGDRARKETLVNYGFRLPSALDNRPLRFEEFEERSPQTIYISATPGPYE
QEHSDNVAEQVVRPTGLIDPEVEIRPVKTQVDDLMSEIRQVIAQGSRILVTTLTKRMAEDLTEYLSEHGIKVRYLHSDVD
TVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVALVAILDADKEGFLRSERSLIQTIGRAARNVKGRAILYADTITGSM
QRALTETERRREKQKAFNLEHGITPKGINKSVEDILEGAYIGKRKTVVAEKSPQYTHWSPQELVKQINALEKQMYSHAQN
MEFELAAKIRDEYLLLKEQLMKI

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=564447 MBG98_RS00380 WP_010945833.1 80123..82114(+) (uvrB) [Legionella pneumophila strain 11052018-5]
ATGAAAGACTTATTTAAAATTTACTCAAATTACCAACCTGCCGGCGATCAACCTACAGCCATAGCCTCTTTGATTGATGG
TCTTGAATCAGGTTTAGCCAAACAAACATTATTAGGCGTTACCGGTTCTGGTAAAACATTTACTATAGCTCATGTTATTC
AAGCCATGAAAAGACCCACTTTGATCATGGCACCGAACAAAACGCTTGCGGCTCAACTTTATGGAGAGTTTAAAGCCTTC
TTTCCTGATAATGCCGTAGAATATTTCGTTTCCTACTACGATTACTATCAGCCCGAAGCGTATGTGCCTGCTTCAGATAC
TTTTATAGAAAAGGATGCCTCCATTAATGAACATATAGAGCAGATGCGCTTGTCGGCAACCAAAGCGTTGATTGAACGCA
AAGATGCCATTATTGTAGCGACGGTTTCTGCCATTTATGGATTGGGCGACCCGGATTCCTATCTGCGTATGTTATTACAT
CTCTCCCGTGGAGAACAATCCGATCAGCGTAAAATTTTAAAGCGTCTTGCAGAAATGCAGTACACACGAACCAATCTCAG
CCTTGAGCGCGGTCAATTCCGGGTACATGGTGATGTCATTGATATTTTCCCGGCTGATTCCGAGAAAGAAGCGATAAGAA
TTGAGCTTTTTGACGATGAGGTTGATAATATTGCCCGCTTTGATCCTTTAACGGGAGAAATTTTACAGCGGTTGCCCCGT
GTCACTATTTTTCCTAAAACTCATTATGTCACTCCCAGAGAACGTATTTTAGAAACAGTAGAAAAAGTAAAAGTAGAATT
ACAGGAAAGGCTGGCTGAGTTGAATGCTCAAAATAAGTTGGTAGAAGCTCAGCGTTTGGAGCAAAGAACTTGTTTTGATA
TTGAAATGATGTTGGAGTTGGGTTATTGCTCTGGCATTGAAAATTACTCGCGTTATTTATCCAACCGCGAAGCAGGGGAA
GCACCGCCTACTCTTTTTGATTATCTCCCGCCCGAAGCCTTGCTAATTATCGACGAATCGCATGTTACTGTTCCTCAAAT
AGGTGGGATGTATCGCGGAGACAGGGCGCGCAAGGAAACCTTGGTTAATTATGGATTTCGCCTGCCTTCTGCCTTGGATA
ATAGGCCTTTGCGTTTTGAAGAATTTGAAGAGCGTTCGCCGCAGACTATTTATATTTCAGCAACTCCAGGGCCTTATGAA
CAGGAACATTCGGATAATGTGGCTGAACAAGTGGTAAGACCGACTGGATTGATTGATCCTGAGGTGGAAATCAGGCCGGT
AAAAACTCAGGTGGATGATCTTATGTCTGAAATCAGACAGGTGATCGCTCAGGGCAGCCGTATTCTTGTCACGACATTAA
CCAAACGCATGGCAGAGGATTTGACAGAGTATCTGAGTGAGCACGGGATCAAGGTGCGCTATTTGCATTCCGACGTCGAT
ACGGTTGAGCGCATGGAAATTATTCGTGATTTGCGTTTGGGTGAGTTTGATGTTCTGGTAGGGATTAATTTATTGCGCGA
AGGTCTTGATATGCCCGAGGTTGCTCTTGTTGCGATTTTGGATGCTGACAAGGAAGGTTTTTTACGATCGGAGCGTTCTT
TAATTCAAACGATTGGCCGTGCAGCGCGTAATGTGAAGGGGCGAGCTATTTTGTATGCCGATACCATTACTGGTTCGATG
CAAAGAGCATTGACGGAAACAGAGAGACGACGTGAAAAGCAAAAAGCATTCAATTTGGAACACGGCATTACTCCCAAGGG
TATTAATAAGTCTGTTGAGGATATTTTGGAAGGTGCCTATATCGGTAAACGAAAAACAGTGGTTGCTGAAAAATCTCCCC
AATATACTCATTGGTCTCCTCAGGAACTGGTAAAACAGATTAATGCGCTCGAAAAACAAATGTATTCTCATGCTCAAAAC
ATGGAATTTGAATTGGCAGCTAAAATTCGCGATGAATACCTGCTATTAAAAGAGCAGTTGATGAAGATATAA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(625-659)

Helicase conserved C-terminal domain (Helicase_C)

(441-543)

Type III restriction enzyme, res subunit (ResIII)

(15-143)

Ultra-violet resistance protein B (UvrB)

(551-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5ZZD9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.641

98.793

0.56
  uvrB Streptococcus pneumoniae R6

56.641

98.793

0.56
  uvrB Streptococcus pneumoniae D39

56.641

98.793

0.56