Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L6L68_RS23100 Genome accession   NZ_CP091673
Coordinates   4553196..4553786 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain KKo009     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4548196..4558786
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6L68_RS23085 (L6L68_23080) uhpT 4548718..4550109 (-) 1392 WP_063091047.1 hexose-6-phosphate:phosphate antiporter -
  L6L68_RS23090 (L6L68_23085) uhpC 4550365..4551684 (-) 1320 WP_001696326.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  L6L68_RS23095 (L6L68_23090) uhpB 4551694..4553196 (-) 1503 WP_001318135.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  L6L68_RS23100 (L6L68_23095) letA 4553196..4553786 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  L6L68_RS23105 (L6L68_23100) ilvN 4553859..4554149 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  L6L68_RS23110 (L6L68_23105) ilvB 4554153..4555841 (-) 1689 WP_000168476.1 acetolactate synthase large subunit -
  L6L68_RS23115 (L6L68_23110) ivbL 4555947..4556045 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  L6L68_RS23120 (L6L68_23115) tisB 4556609..4556698 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  L6L68_RS23125 (L6L68_23120) ysdE 4556822..4556896 (-) 75 WP_211180519.1 protein YsdE -
  L6L68_RS23130 (L6L68_23125) emrD 4556978..4558162 (+) 1185 WP_001696327.1 multidrug efflux MFS transporter EmrD -
  L6L68_RS23135 (L6L68_23130) yidF 4558170..4558667 (-) 498 WP_000148034.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=562741 L6L68_RS23100 WP_000633668.1 4553196..4553786(-) (letA) [Escherichia coli strain KKo009]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=562741 L6L68_RS23100 WP_000633668.1 4553196..4553786(-) (letA) [Escherichia coli strain KKo009]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378