Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   L6L68_RS19815 Genome accession   NZ_CP091673
Coordinates   3884010..3884669 (+) Length   219 a.a.
NCBI ID   WP_001221486.1    Uniprot ID   -
Organism   Escherichia coli strain KKo009     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3879010..3889669
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6L68_RS19800 (L6L68_19800) ygiS 3881215..3882822 (-) 1608 WP_040234936.1 ABC transporter substrate-binding protein -
  L6L68_RS19805 (L6L68_19805) ygiV 3882931..3883413 (-) 483 WP_000183494.1 GyrI-like domain-containing protein -
  L6L68_RS19810 (L6L68_19810) ygiW 3883466..3883858 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  L6L68_RS19815 (L6L68_19815) ciaR 3884010..3884669 (+) 660 WP_001221486.1 quorum sensing response regulator transcription factor QseB Regulator
  L6L68_RS19820 (L6L68_19820) qseC 3884666..3886015 (+) 1350 WP_000673348.1 quorum sensing histidine kinase QseC -
  L6L68_RS19825 (L6L68_19825) ygiZ 3886061..3886393 (-) 333 WP_000912091.1 DUF2645 family protein -
  L6L68_RS19830 (L6L68_19830) mdaB 3886751..3887332 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  L6L68_RS19835 (L6L68_19835) ygiN 3887363..3887677 (+) 315 WP_000958598.1 putative quinol monooxygenase -
  L6L68_RS19840 (L6L68_19840) parE 3887725..3889617 (-) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24692.61 Da        Isoelectric Point: 6.3527

>NTDB_id=562727 L6L68_RS19815 WP_001221486.1 3884010..3884669(+) (ciaR) [Escherichia coli strain KKo009]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGCQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=562727 L6L68_RS19815 WP_001221486.1 3884010..3884669(+) (ciaR) [Escherichia coli strain KKo009]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTTGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365