Detailed information NTG0056265

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SAJPND1_RS08555
• Genome accession: NZ_AP014652
• Coordinates: 1757235..1758224 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain TMUS2126
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1752235..1763224

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAJPND1_RS08540 (AXW71_RS08540)	acsA	1753436..1755142 (-)	1707	WP_000862084.1	acetate--CoA ligase	-
SAJPND1_RS08545 (AXW71_RS08545)	-	1755311..1755943 (+)	633	WP_001016008.1	GNAT family N-acetyltransferase	-
SAJPND1_RS08550 (AXW71_RS08550)	-	1755968..1757137 (+)	1170	WP_001184008.1	acetoin utilization protein AcuC	-
SAJPND1_RS08555 (AXW71_RS08555)	ccpA	1757235..1758224 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
SAJPND1_RS08560 (AXW71_RS08560)	-	1758297..1758410 (-)	114	WP_001788994.1	hypothetical protein	-
SAJPND1_RS08565 (AXW71_RS08565)	-	1758764..1759855 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
SAJPND1_RS08570 (AXW71_RS08570)	-	1760316..1760399 (-)	84	WP_031789490.1	hypothetical protein	-
SAJPND1_RS08575 (AXW71_RS08575)	-	1760555..1761907 (-)	1353	WP_000193924.1	hypothetical protein	-
SAJPND1_RS08580 (AXW71_RS08580)	-	1761981..1762472 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=56265 SAJPND1_RS08555 WP_000219066.1 1757235..1758224(-) (ccpA) [Staphylococcus aureus strain TMUS2126]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=56265 SAJPND1_RS08555 WP_000219066.1 1757235..1758224(-) (ccpA) [Staphylococcus aureus strain TMUS2126]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGTCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGTAATCTTCCAGATGCTATA
TTATGTATCAGTGACGAAGAAGCTATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGTTTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462