Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | KFV48_RS00610 | Genome accession | NZ_CP073855 |
| Coordinates | 109614..110960 (-) | Length | 448 a.a. |
| NCBI ID | WP_000816499.1 | Uniprot ID | Q9R3W9 |
| Organism | Staphylococcus epidermidis strain B1269488 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 62299..110960 | 109614..110960 | within | 0 |
Gene organization within MGE regions
Location: 62299..110960
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFV48_RS00355 (KFV48_00355) | ccrB | 62299..63927 (-) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
| KFV48_RS00360 (KFV48_00360) | ccrA | 63924..65285 (-) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| KFV48_RS00365 (KFV48_00365) | - | 65472..66101 (-) | 630 | Protein_54 | hypothetical protein | - |
| KFV48_RS00370 (KFV48_00370) | - | 66110..66448 (+) | 339 | Protein_55 | recombinase family protein | - |
| KFV48_RS00375 (KFV48_00375) | - | 66560..66919 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| KFV48_RS00380 (KFV48_00380) | - | 67126..67452 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV48_RS00385 (KFV48_00385) | - | 67782..69707 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| KFV48_RS00390 (KFV48_00390) | - | 70959..71264 (+) | 306 | WP_000677987.1 | hypothetical protein | - |
| KFV48_RS00395 (KFV48_00395) | - | 71462..72325 (+) | 864 | WP_000680579.1 | hypothetical protein | - |
| KFV48_RS00400 (KFV48_00400) | - | 72433..73908 (+) | 1476 | WP_001138664.1 | DUF6038 family protein | - |
| KFV48_RS00405 (KFV48_00405) | - | 74135..75235 (+) | 1101 | WP_000449985.1 | DNA polymerase | - |
| KFV48_RS00410 (KFV48_00410) | - | 75228..75599 (+) | 372 | WP_001058157.1 | hypothetical protein | - |
| KFV48_RS00415 (KFV48_00415) | - | 75596..77239 (+) | 1644 | WP_012086574.1 | DUF5906 domain-containing protein | - |
| KFV48_RS00420 (KFV48_00420) | - | 77466..79142 (+) | 1677 | WP_012086571.1 | recombinase family protein | - |
| KFV48_RS00425 (KFV48_00425) | - | 79248..79586 (+) | 339 | WP_012086569.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV48_RS00430 (KFV48_00430) | - | 79682..79993 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| KFV48_RS00435 (KFV48_00435) | - | 80009..80515 (+) | 507 | WP_012086564.1 | DUF1643 domain-containing protein | - |
| KFV48_RS00440 (KFV48_00440) | - | 80543..80989 (+) | 447 | WP_012086562.1 | JAB domain-containing protein | - |
| KFV48_RS00445 (KFV48_00445) | - | 81159..82031 (+) | 873 | WP_012086560.1 | HTH domain-containing protein | - |
| KFV48_RS00450 (KFV48_00450) | - | 82083..82373 (+) | 291 | WP_012086558.1 | hypothetical protein | - |
| KFV48_RS00460 (KFV48_00460) | - | 82596..82751 (+) | 156 | Protein_72 | metal-sensing transcriptional repressor | - |
| KFV48_RS00465 (KFV48_00465) | - | 82748..83506 (+) | 759 | WP_000623679.1 | sulfite exporter TauE/SafE family protein | - |
| KFV48_RS00470 (KFV48_00470) | - | 83676..83885 (+) | 210 | Protein_74 | heavy metal translocating P-type ATPase | - |
| KFV48_RS00475 (KFV48_00475) | - | 83903..84448 (+) | 546 | WP_031869236.1 | YdhK family protein | - |
| KFV48_RS00480 (KFV48_00480) | - | 84891..86147 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| KFV48_RS00485 (KFV48_00485) | - | 86592..87266 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| KFV48_RS00490 (KFV48_00490) | - | 87350..87691 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| KFV48_RS00495 (KFV48_00495) | - | 88488..89231 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| KFV48_RS00500 (KFV48_00500) | - | 89328..89756 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| KFV48_RS00505 (KFV48_00505) | mecA | 89802..91811 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| KFV48_RS00510 (KFV48_00510) | mecR1 | 91908..93665 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KFV48_RS00515 (KFV48_00515) | mecI | 93665..94036 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KFV48_RS00520 (KFV48_00520) | psm-mec | 94121..94189 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KFV48_RS00525 (KFV48_00525) | - | 94544..95653 (+) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| KFV48_RS00530 (KFV48_00530) | cstB | 95767..97101 (-) | 1335 | Protein_86 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KFV48_RS00535 (KFV48_00535) | - | 97134..98198 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KFV48_RS00540 (KFV48_00540) | cstR | 98334..98594 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KFV48_RS00545 (KFV48_00545) | - | 98594..99232 (+) | 639 | Protein_89 | sulfite exporter TauE/SafE family protein | - |
| KFV48_RS00555 (KFV48_00555) | - | 99506..100122 (-) | 617 | Protein_90 | CadD family cadmium resistance transporter | - |
| KFV48_RS00560 (KFV48_00560) | - | 100203..102617 (-) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| KFV48_RS00565 (KFV48_00565) | - | 102610..102975 (-) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV48_RS00570 (KFV48_00570) | - | 103213..103590 (-) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| KFV48_RS00575 (KFV48_00575) | - | 103597..105489 (-) | 1893 | WP_002485298.1 | site-specific integrase | - |
| KFV48_RS00580 (KFV48_00580) | - | 105684..106007 (-) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| KFV48_RS00585 (KFV48_00585) | - | 106000..106206 (-) | 207 | WP_001077283.1 | hypothetical protein | - |
| KFV48_RS00590 (KFV48_00590) | - | 106208..106729 (-) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| KFV48_RS00595 (KFV48_00595) | - | 106748..107059 (-) | 312 | WP_000833212.1 | DUF960 family protein | - |
| KFV48_RS00600 (KFV48_00600) | - | 107144..107494 (-) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV48_RS00605 (KFV48_00605) | ccrB | 107965..109593 (-) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| KFV48_RS00610 (KFV48_00610) | ccrA | 109614..110960 (-) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 448 a.a. Molecular weight: 52138.19 Da Isoelectric Point: 10.1760
>NTDB_id=561456 KFV48_RS00610 WP_000816499.1 109614..110960(-) (ccrA) [Staphylococcus epidermidis strain B1269488]
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
Nucleotide
Download Length: 1347 bp
>NTDB_id=561456 KFV48_RS00610 WP_000816499.1 109614..110960(-) (ccrA) [Staphylococcus epidermidis strain B1269488]
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
78.174 |
100 |
0.783 |
| ccrA | Staphylococcus aureus N315 |
72.383 |
100 |
0.725 |