Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L3Z43_RS21935 Genome accession   NZ_CP091427
Coordinates   4575770..4576360 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 1000C-3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4570770..4581360
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3Z43_RS21920 uhpT 4571410..4572801 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  L3Z43_RS21925 uhpC 4572939..4574258 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  L3Z43_RS21930 uhpB 4574268..4575770 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  L3Z43_RS21935 letA 4575770..4576360 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  L3Z43_RS21940 ilvN 4576435..4576725 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  L3Z43_RS21945 ilvB 4576729..4578417 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  L3Z43_RS21950 ivbL 4578523..4578621 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  L3Z43_RS21955 - 4579013..4580233 (+) 1221 WP_000343760.1 ISL3-like element ISKox3 family transposase -
  L3Z43_RS21960 tisB 4580510..4580599 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  L3Z43_RS21965 ysdE 4580723..4580797 (-) 75 WP_211180519.1 protein YsdE -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=561353 L3Z43_RS21935 WP_000633668.1 4575770..4576360(-) (letA) [Escherichia coli strain 1000C-3]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=561353 L3Z43_RS21935 WP_000633668.1 4575770..4576360(-) (letA) [Escherichia coli strain 1000C-3]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378