Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   SCSC_RS05320 Genome accession   NZ_AP014647
Coordinates   1073897..1075249 (-) Length   450 a.a.
NCBI ID   WP_006270686.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. constellatus strain CCUG 24889     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1068897..1080249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCSC_RS05305 (SCSC_1096) rnc 1071911..1072609 (-) 699 WP_006270710.1 ribonuclease III -
  SCSC_RS05310 - 1072745..1073058 (-) 314 Protein_1029 YbaN family protein -
  SCSC_RS05315 (SCSC_1098) vicX 1073092..1073895 (-) 804 WP_006270665.1 MBL fold metallo-hydrolase Regulator
  SCSC_RS05320 (SCSC_1099) micB 1073897..1075249 (-) 1353 WP_006270686.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SCSC_RS05325 (SCSC_1100) yycF 1075242..1075943 (-) 702 WP_003035055.1 response regulator YycF -
  SCSC_RS05330 (SCSC_1101) - 1076244..1076576 (-) 333 WP_006268722.1 hypothetical protein -
  SCSC_RS05335 (SCSC_1102) - 1076603..1077916 (-) 1314 WP_006268747.1 glycosyltransferase family 4 protein -
  SCSC_RS05340 (SCSC_1103) - 1077918..1078916 (-) 999 WP_003068685.1 glycosyltransferase -
  SCSC_RS05345 (SCSC_1104) ccpA 1079008..1080012 (-) 1005 WP_006270669.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51400.71 Da        Isoelectric Point: 4.7721

>NTDB_id=55971 SCSC_RS05320 WP_006270686.1 1073897..1075249(-) (micB) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MIDNIRQFVVSRDFVFVLLILGFILVITLLSLENRRDNIRIRRLNQKVKDLIAGDYSEVLDMQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDVEDEYDLRDLITKVPV
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVGMKTTETQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHHGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=55971 SCSC_RS05320 WP_006270686.1 1073897..1075249(-) (micB) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGATTGATAATATTAGACAATTTGTTGTATCAAGGGATTTTGTTTTTGTCTTACTTATTTTAGGATTTATTTTGGTCAT
TACGCTGCTCTCCTTGGAAAACAGACGTGATAATATTCGTATTCGCCGATTGAATCAAAAGGTGAAGGATTTAATCGCGG
GAGATTATTCAGAAGTTTTAGATATGCAAGGTGGTCCGGAAATTACTGATATTACAAATAGTATCAATGACTTATCTGAG
GTAATTCGCCTAACGCATGAAAATTTAGAGCAAGAAACCAAACGCTTGTCTAGTATTTTGTCCTATATGACAGATGGCGT
TCTTGCGACCAATCGTCGTGGGCAGATTATTATGATTAATGATATGGCGACCAAGCAATTGGGAGTCAAAGAATCTGAAG
CACGAAAGATGAATATCTTAAAATTGTTGGATGTTGAAGACGAATATGATTTACGAGACTTGATTACGAAAGTTCCAGTG
TTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTCCGATTTGCCTTGATTCGTCGAGAGTCAGG
CTTTATTTCAGGGCTGGTTGCTGTGCTGCACGATACAACGGAGCAGGAGAAAGAGGAGCGTGAGCGGAGACTATTTGTTT
CCAATGTTAGTCATGAATTGCGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCATTAGATGAAGGTGCCTTGTCA
GAACCAGTCGCACCAGATTTTATTAAGGTTTCGTTAGATGAAACCAATCGGATGATGCGAATGGTTTCAGACTTGCTGAG
TTTGTCACGTATTGACAATGCTACCAGTCATTTGGATATTGAGCTGACGAATTTTACAGCTTTTATCACGTTTATTTTAA
ATCGTTTTGACAAAATCAGAAGTCAGAATGATGATAAAAAATATGAAATCATTCGTGATTACCCCATTAACTCCATCTGG
GTTGAAATTGATACGGATAAGATGACACAGGTTATTGATAATATCATCAATAATGCTATTAAATATTCTCCTGACGGCGG
TAAGATCACAGTGGGTATGAAAACAACCGAGACCCAAATGATTTTGTCTATATCAGATGAGGGCTTAGGAATTCCCAAAA
AAGATTTACCGAAAATTTTTGACCGCTTCTATCGTGTAGACAAAGCAAGAAGTCGTGCACAAGGTGGATCCGGATTAGGT
TTAGCTATTGCTAAGGAAATTATTAAGCAACATCACGGATTTATCTGGGCAAAGAGCGAGTATGGCAAAGGCTCAACCTT
TACTATTGTCCTGCCTTATGATAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGGTAG

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

81.321

97.556

0.793
  vicK Streptococcus mutans UA159

70.905

90.889

0.644

Multiple sequence alignment