Detailed information NTG0558181

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: KCG51_RS10680
• Genome accession: NZ_CP073119
• Coordinates: 2262200..2262601 (-)
• Length: 133 a.a.
• NCBI ID: WP_349306335.1
• Uniprot ID: -
• Organism: Neisseria subflava strain HP0069
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	2242844..2262491	2262200..2262601	flank	-291
IScluster/Tn	2262638..2263644	2262200..2262601	flank	37

Gene organization within MGE regions

Location: 2242844..2263644

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KCG51_RS10610 (KCG51_10635)	-	2242844..2244859 (-)	2016	WP_250581003.1	DUF2235 domain-containing protein	-
KCG51_RS10615 (KCG51_10640)	-	2244881..2245393 (-)	513	WP_250581004.1	DUF3304 domain-containing protein	-
KCG51_RS10620 (KCG51_10645)	-	2245459..2246229 (-)	771	WP_250581005.1	hypothetical protein	-
KCG51_RS10625 (KCG51_10650)	vgrG	2246229..2248580 (-)	2352	WP_250581006.1	type VI secretion system tip protein VgrG	-
KCG51_RS10630 (KCG51_10655)	tssH	2248725..2251544 (-)	2820	WP_250580090.1	type VI secretion system ATPase TssH	-
KCG51_RS10635 (KCG51_10660)	-	2251616..2252104 (-)	489	WP_070589483.1	Hcp family type VI secretion system effector	-
KCG51_RS10640 (KCG51_10665)	-	2252175..2253803 (-)	1629	WP_250580091.1	OmpA family protein	-
KCG51_RS10645 (KCG51_10670)	-	2253821..2254483 (-)	663	WP_250580093.1	DotU/TssL family secretion system protein	-
KCG51_RS10650 (KCG51_10675)	tssK	2254485..2255831 (-)	1347	WP_250580094.1	type VI secretion system baseplate subunit TssK	-
KCG51_RS10655 (KCG51_10680)	tssB	2255991..2256491 (+)	501	WP_254342298.1	type VI secretion system contractile sheath small subunit	-
KCG51_RS10660 (KCG51_10685)	tssC	2256676..2258064 (+)	1389	WP_254342559.1	type VI secretion system contractile sheath large subunit	-
KCG51_RS10665 (KCG51_10690)	-	2258117..2258380 (-)	264	WP_049332348.1	PAAR domain-containing protein	-
KCG51_RS10670 (KCG51_10695)	-	2258429..2259574 (-)	1146	WP_250581007.1	hypothetical protein	-
KCG51_RS10675 (KCG51_10700)	uvrB	2259924..2261951 (-)	2028	WP_250581008.1	excinuclease ABC subunit UvrB	-
KCG51_RS10680 (KCG51_10705)	comP	2262200..2262601 (-)	402	WP_349306335.1	type IV pilin protein	Machinery gene
KCG51_RS10685 (KCG51_10710)	-	2262638..2263644 (+)	1007	Protein_2063	IS5 family transposase	-

Sequence

Protein

• Length: 133 a.a.
• Molecular weight: 14652.97 Da
• Isoelectric Point: 9.9040

>NTDB_id=558181 KCG51_RS10680 WP_349306335.1 2262200..2262601(-) (comP) [Neisseria subflava strain HP0069]
MLGNFAKVSAYRESVRSANLRAAHAALLENARFMEQFYMKKGSFKLTSTKWPELPVKEAGGFCIRMSGQAKGILEGKFTL
KAVALDREAEPRVLRLNESLTAVVCGKMKGKGNCTDGEEIFRGNDAECRPFTG

Nucleotide

• Length: 402 bp

>NTDB_id=558181 KCG51_RS10680 WP_349306335.1 2262200..2262601(-) (comP) [Neisseria subflava strain HP0069]
ATTTTGGGGAATTTTGCAAAGGTCTCGGCCTATCGGGAATCGGTCCGCTCGGCCAACCTGCGTGCGGCGCATGCCGCCCT
GCTGGAAAATGCGCGCTTTATGGAGCAGTTCTACATGAAAAAGGGCAGCTTTAAGCTGACGTCGACGAAGTGGCCGGAGC
TGCCGGTAAAGGAGGCGGGTGGTTTCTGTATCAGGATGAGCGGCCAGGCTAAGGGGATCTTGGAGGGGAAGTTTACTTTG
AAGGCGGTGGCGCTGGACAGGGAAGCGGAGCCGAGGGTATTGCGCTTGAACGAGTCGCTGACGGCGGTGGTGTGCGGGAA
AATGAAGGGGAAGGGAAACTGTACTGACGGCGAGGAGATATTTAGGGGCAATGATGCGGAGTGCCGGCCTTTTACGGGGT
AG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (10-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria subflava NJ9703	95.312	96.241	0.917
comP	Neisseria meningitidis 8013	51.639	91.729	0.474
comP	Neisseria gonorrhoeae MS11	51.667	90.226	0.466