Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   L1O91_RS03450 Genome accession   NZ_CP091066
Coordinates   736436..738421 (+) Length   661 a.a.
NCBI ID   WP_000229253.1    Uniprot ID   A0A0H2XGZ8
Organism   Staphylococcus aureus strain UMCG579     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 731436..743421
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1O91_RS03420 (L1O91_03420) - 732481..732578 (+) 98 Protein_660 hypothetical protein -
  L1O91_RS03425 (L1O91_03425) prfB 732753..733863 (+) 1111 WP_100793797.1 peptide chain release factor 2 -
  L1O91_RS03430 (L1O91_03430) - 734037..734123 (+) 87 WP_016187770.1 hypothetical protein -
  L1O91_RS03435 (L1O91_03435) - 734271..735110 (+) 840 WP_054189270.1 CHAP domain-containing protein -
  L1O91_RS03440 (L1O91_03440) - 735284..735934 (+) 651 WP_000538141.1 YfbR-like 5'-deoxynucleotidase -
  L1O91_RS03445 (L1O91_03445) - 735931..736167 (+) 237 WP_000638419.1 CsbA family protein -
  L1O91_RS03450 (L1O91_03450) uvrB 736436..738421 (+) 1986 WP_000229253.1 excinuclease ABC subunit UvrB Machinery gene
  L1O91_RS03455 (L1O91_03455) uvrA 738429..741275 (+) 2847 WP_054191853.1 excinuclease ABC subunit UvrA Machinery gene
  L1O91_RS03460 (L1O91_03460) hprK 741937..742869 (+) 933 WP_000958224.1 HPr(Ser) kinase/phosphatase -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 76648.34 Da        Isoelectric Point: 5.0538

>NTDB_id=558017 L1O91_RS03450 WP_000229253.1 736436..738421(+) (uvrB) [Staphylococcus aureus strain UMCG579]
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFK
EFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKER
EHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPL
GSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGP
YEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSE
IKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTD
SMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAK
DLDFEKATELRDMLFELKAEG

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=558017 L1O91_RS03450 WP_000229253.1 736436..738421(+) (uvrB) [Staphylococcus aureus strain UMCG579]
ATGGTTGAACATTATCCTTTTAAAATACATTCTGATTTTGAGCCTCAAGGTGACCAACCACAAGCAATTAAGGAAATCGT
GGAAGGTATTAAAGCGGGGAAAAGACATCAAACTTTATTAGGTGCAACTGGCACAGGGAAAACATTTACGATGAGTAATG
TTATTAAAGAAGTTGGGAAACCAACGTTAATTATCGCGCATAACAAAACATTAGCAGGACAATTATATAGTGAGTTTAAA
GAATTTTTTCCTGAAAACAGGGTGGAATACTTTGTAAGTTACTATGATTATTATCAACCTGAGGCATACGTACCGTCTAC
TGACACTTTTATTGAAAAAGATGCCTCAATCAATGATGAAATTGATCAACTACGACATTCTGCTACAAGTGCATTATTTG
AACGCGATGATGTAATTATTATTGCTAGTGTAAGTTGTATATATGGTTTAGGTAATCCTGAAGAATATAAAGATTTAGTA
GTAAGTGTTCGAGTTGGTATGGAAATGGATAGAAGTGAATTACTTAGAAAACTTGTAGATGTGCAATATACACGAAATGA
CATCGATTTCCAACGAGGAACGTTTCGAGTGCGTGGTGATGTAGTTGAAATATTCCCAGCCTCTAAAGAAGAACTTTGTA
TAAGGGTTGAGTTTTTCGGCGATGAGATTGACCGTATTCGAGAAGTTAACTACCTAACTGGTGAAGTGTTGAAAGAAAGA
GAACATTTTGCGATATTCCCAGCTTCTCACTTCGTAACACGTGAAGAAAAGTTGAAAGTTGCGATTGAACGTATTGAAAA
AGAATTGGAAGAACGATTGAAAGAATTACGAGATGAGAATAAATTACTAGAAGCGCAAAGGTTAGAACAGCGTACCAACT
ATGATTTAGAAATGATGCGAGAAATGGGATTCTGTTCAGGAATTGAAAACTATTCAGTACATTTAACGTTGCGACCACTA
GGTTCGACACCATATACTTTATTGGATTACTTTGGCGATGATTGGTTAGTAATGATTGATGAATCACATGTGACGTTACC
GCAAGTTCGTGGCATGTATAACGGAGACAGAGCACGAAAACAAGTTTTAGTTGATCATGGATTTAGATTACCAAGTGCGT
TAGATAACCGCCCACTTAAATTTGAAGAATTTGAAGAAAAGACGAAACAACTTGTGTATGTATCTGCAACGCCTGGTCCA
TACGAAATTGAACATACGGATAAGATGGTTGAACAAATTATTCGTCCTACTGGTTTACTGGATCCTAAGATTGAGGTTAG
ACCTACTGAAAATCAAATTGACGATTTATTAAGTGAAATTCAAACAAGAGTTGAGCGTAATGAAAGAGTACTTGTTACAA
CGCTCACTAAAAAGATGAGTGAAGATTTAACCACATATATGAAAGAAGCAGGCATTAAAGTTAACTATCTACATTCTGAA
ATTAAAACATTAGAACGAATCGAAATAATTAGAGACTTACGAATGGGTACATATGATGTTATCGTAGGTATTAATTTATT
AAGAGAGGGTATTGATATACCAGAAGTTTCTCTAGTTGTCATATTAGATGCAGATAAAGAAGGATTTTTACGTTCTAACC
GCTCATTAATTCAAACAATAGGTAGAGCTGCGCGTAACGATAAAGGTGAAGTCATTATGTATGCCGATAAAATGACTGAT
TCGATGAAGTATGCAATTGATGAGACACAACGTCGTCGAGAAATACAGATGAAACATAATGAAAAACATGGTATTACACC
TAAAACAATTAATAAAAAAATACATGATTTAATTAGTGCTACTGTTGAAAATGACGAAAATAATGACAAAGCACAAACTG
TGATACCTAAGAAGATGACGAAAAAAGAACGTCAAAAGACAATCGACAATATAGAAAAAGAAATGAAACAAGCAGCGAAA
GATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAAAGCAGAAGGGTGA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(434-546)

Ultra-violet resistance protein B (UvrB)

(553-594)

Type III restriction enzyme, res subunit (ResIII)

(14-140)

UvrB/uvrC motif (UVR)

(626-659)

UvrB interaction domain (UvrB_inter)

(161-251)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XGZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

67.534

98.79

0.667
  uvrB Streptococcus pneumoniae TIGR4

67.534

98.79

0.667
  uvrB Streptococcus pneumoniae D39

67.534

98.79

0.667