Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L1123_RS18735 Genome accession   NZ_CP091065
Coordinates   3842666..3843256 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain DOC14     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3837666..3848256
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1123_RS18720 (L1123_18720) uhpT 3838306..3839697 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  L1123_RS18725 (L1123_18725) uhpC 3839835..3841154 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  L1123_RS18730 (L1123_18730) uhpB 3841164..3842666 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  L1123_RS18735 (L1123_18735) letA 3842666..3843256 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  L1123_RS18740 (L1123_18740) ilvN 3843332..3843622 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  L1123_RS18745 (L1123_18745) ilvB 3843626..3845314 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  L1123_RS18750 (L1123_18750) ivbL 3845420..3845518 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  L1123_RS18755 (L1123_18755) tisB 3846083..3846172 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  L1123_RS18760 (L1123_18760) ysdE 3846296..3846370 (-) 75 WP_211180519.1 protein YsdE -
  L1123_RS18765 (L1123_18765) emrD 3846452..3847636 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  L1123_RS18770 (L1123_18770) yidF 3847644..3848141 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=557980 L1123_RS18735 WP_000633668.1 3842666..3843256(-) (letA) [Escherichia coli strain DOC14]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=557980 L1123_RS18735 WP_000633668.1 3842666..3843256(-) (letA) [Escherichia coli strain DOC14]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378