Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   INT76_RS09745 Genome accession   NZ_CP073084
Coordinates   1940719..1941408 (+) Length   229 a.a.
NCBI ID   WP_212570312.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1935719..1946408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS09720 (INT76_09720) - 1936108..1937451 (+) 1344 WP_212570301.1 DEAD/DEAH box helicase -
  INT76_RS09725 (INT76_09725) - 1937467..1937691 (+) 225 WP_212570303.1 DUF4059 family protein -
  INT76_RS09730 (INT76_09730) trxB 1937705..1938622 (+) 918 WP_212570305.1 thioredoxin-disulfide reductase -
  INT76_RS09735 (INT76_09735) - 1938633..1939175 (+) 543 WP_212570307.1 DUF177 domain-containing protein -
  INT76_RS09740 (INT76_09740) gndA 1939291..1940715 (+) 1425 WP_212570310.1 NADP-dependent phosphogluconate dehydrogenase -
  INT76_RS09745 (INT76_09745) covR 1940719..1941408 (+) 690 WP_212570312.1 winged helix-turn-helix domain-containing protein Regulator
  INT76_RS09750 (INT76_09750) - 1941496..1942608 (+) 1113 WP_212570314.1 AI-2E family transporter -
  INT76_RS09755 (INT76_09755) - 1942766..1944298 (+) 1533 WP_212570316.1 hypothetical protein -
  INT76_RS09760 (INT76_09760) nrdR 1944392..1944865 (+) 474 WP_212570318.1 transcriptional regulator NrdR -
  INT76_RS09765 (INT76_09765) - 1944869..1946032 (+) 1164 WP_212570326.1 replication initiation/membrane attachment protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26135.08 Da        Isoelectric Point: 6.1338

>NTDB_id=557867 INT76_RS09745 WP_212570312.1 1940719..1941408(+) (covR) [Streptococcus oriscaviae strain HKU75]
MAKKILIAGRERNLSHFVSMELQKKDYLVDYASTGKEALLLAHETDFDLILMSFQLSDMSSKELSKELLKLKPASVIIVA
VDSADVAAHGQDILTYAVSYVIKPFVISDLVEQVTAIFRGRDFIDENCKQVKLHAAYRDLKIDFQNRTVSRGDELINLTR
REYDLLATLMNSPETMSREQLLDRVWKYESAAETNVVDVYIRYLRGKLDLPGQESYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=557867 INT76_RS09745 WP_212570312.1 1940719..1941408(+) (covR) [Streptococcus oriscaviae strain HKU75]
ATGGCCAAAAAGATTCTAATTGCAGGTAGAGAGCGTAACCTGTCTCACTTCGTTTCCATGGAATTGCAGAAGAAGGACTA
TCTCGTTGACTATGCTTCAACAGGAAAGGAAGCTCTCTTACTAGCACATGAAACGGACTTTGATTTGATATTGATGAGTT
TTCAACTGTCGGACATGTCCAGCAAGGAACTGTCTAAAGAGTTGCTCAAACTCAAACCCGCTTCTGTTATCATCGTGGCT
GTGGATAGTGCAGATGTTGCTGCCCATGGTCAGGACATATTGACCTATGCTGTTTCTTATGTTATCAAACCTTTCGTGAT
TAGTGATTTGGTTGAGCAAGTGACAGCCATCTTTCGCGGGCGGGATTTTATCGACGAAAATTGCAAACAGGTCAAGCTTC
ACGCGGCCTACCGTGATTTGAAAATTGATTTCCAAAACCGCACGGTGTCGCGCGGAGATGAGCTCATCAACCTAACCCGA
AGGGAATATGATCTCTTGGCGACGCTGATGAACAGTCCTGAAACCATGAGCCGCGAACAGCTCTTGGATCGGGTTTGGAA
ATATGAGTCGGCAGCAGAAACAAATGTTGTGGACGTCTATATCCGTTACCTAAGAGGCAAGCTGGATCTGCCAGGGCAGG
AGTCCTATATCAAGACTGTCCGTGGAGTTGGCTATGCCATGCGGGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(6-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

50.431

100

0.511
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.121

100

0.467
  vicR Streptococcus mutans UA159

35.169

100

0.362