Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   L1P14_RS03485 Genome accession   NZ_CP091029
Coordinates   710077..710736 (-) Length   219 a.a.
NCBI ID   WP_001221502.1    Uniprot ID   B7LGG8
Organism   Escherichia coli strain STEC384     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 705077..715736
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1P14_RS03460 parE 705168..707060 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  L1P14_RS03465 ygiN 707108..707422 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  L1P14_RS03470 mdaB 707453..708034 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  L1P14_RS03475 ygiZ 708353..708685 (+) 333 WP_137462509.1 DUF2645 family protein -
  L1P14_RS03480 qseC 708731..710080 (-) 1350 WP_000673354.1 quorum sensing histidine kinase QseC -
  L1P14_RS03485 ciaR 710077..710736 (-) 660 WP_001221502.1 quorum sensing response regulator transcription factor QseB Regulator
  L1P14_RS03490 ygiW 710888..711280 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  L1P14_RS03495 ygiV 711333..711815 (+) 483 WP_000183494.1 AraC family transcriptional regulator -
  L1P14_RS03500 parC 712361..714619 (+) 2259 WP_001281881.1 DNA topoisomerase IV subunit A -
  L1P14_RS03505 plsC 714853..715590 (+) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24745.66 Da        Isoelectric Point: 6.6543

>NTDB_id=557768 L1P14_RS03485 WP_001221502.1 710077..710736(-) (ciaR) [Escherichia coli strain STEC384]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=557768 L1P14_RS03485 WP_001221502.1 710077..710736(-) (ciaR) [Escherichia coli strain STEC384]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7LGG8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365