Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L1O93_RS00170 Genome accession   NZ_CP091022
Coordinates   30592..31182 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain STEC276     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 25592..36182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1O93_RS00135 yidF 25708..26205 (+) 498 WP_000148063.1 radical SAM protein -
  L1O93_RS00140 emrD 26213..27397 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  L1O93_RS00145 ysdE 27479..27553 (+) 75 WP_211180519.1 protein YsdE -
  L1O93_RS00150 tisB 27677..27766 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  L1O93_RS00155 ivbL 28331..28429 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  L1O93_RS00160 ilvB 28535..30223 (+) 1689 WP_000168464.1 acetolactate synthase large subunit -
  L1O93_RS00165 ilvN 30227..30517 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  L1O93_RS00170 letA 30592..31182 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  L1O93_RS00175 uhpB 31182..32684 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  L1O93_RS00180 uhpC 32694..34013 (+) 1320 WP_000936560.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  L1O93_RS00185 uhpT 34151..35542 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=557512 L1O93_RS00170 WP_000633668.1 30592..31182(+) (letA) [Escherichia coli strain STEC276]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=557512 L1O93_RS00170 WP_000633668.1 30592..31182(+) (letA) [Escherichia coli strain STEC276]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378