Detailed information NTG0556136

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: L1A04_RS02060
• Genome accession: NZ_CP090879
• Coordinates: 386581..388566 (-)
• Length: 661 a.a.
• NCBI ID: WP_000229253.1
• Uniprot ID: A0A0H2XGZ8
• Organism: Staphylococcus aureus strain SAUR_BFS2
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 381581..393566

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A04_RS02050 (L1A04_02050)	hprK	382184..383116 (-)	933	WP_000958224.1	HPr(Ser) kinase/phosphatase	-
L1A04_RS02055 (L1A04_02055)	uvrA	383727..386573 (-)	2847	WP_000662687.1	excinuclease ABC subunit UvrA	Machinery gene
L1A04_RS02060 (L1A04_02060)	uvrB	386581..388566 (-)	1986	WP_000229253.1	excinuclease ABC subunit UvrB	Machinery gene
L1A04_RS02065 (L1A04_02065)	-	388835..389071 (-)	237	WP_000638419.1	CsbA family protein	-
L1A04_RS02070 (L1A04_02070)	-	389068..389718 (-)	651	WP_000538141.1	YfbR-like 5'-deoxynucleotidase	-
L1A04_RS02075 (L1A04_02075)	-	389892..390731 (-)	840	WP_000749385.1	CHAP domain-containing protein	-
L1A04_RS02085 (L1A04_02085)	-	392785..392883 (-)	99	WP_001791369.1	hypothetical protein	-

Sequence

Protein

• Length: 661 a.a.
• Molecular weight: 76648.34 Da
• Isoelectric Point: 5.0538

>NTDB_id=556136 L1A04_RS02060 WP_000229253.1 386581..388566(-) (uvrB) [Staphylococcus aureus strain SAUR_BFS2]
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFK
EFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKER
EHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPL
GSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGP
YEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSE
IKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTD
SMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAK
DLDFEKATELRDMLFELKAEG

Nucleotide

• Length: 1986 bp

>NTDB_id=556136 L1A04_RS02060 WP_000229253.1 386581..388566(-) (uvrB) [Staphylococcus aureus strain SAUR_BFS2]
ATGGTTGAACATTATCCTTTTAAAATACATTCTGATTTTGAGCCTCAAGGTGACCAACCGCAAGCAATTAAGGAAATCGT
GGAAGGTATTAAAGCGGGGAAAAGACATCAAACTTTATTAGGTGCAACTGGCACAGGGAAAACATTTACGATGAGTAATG
TTATTAAAGAAGTTGGGAAACCAACGTTAATTATCGCGCATAACAAAACATTAGCAGGACAATTATATAGTGAGTTTAAA
GAATTTTTTCCTGAAAACAGGGTGGAATACTTTGTAAGTTACTATGATTATTATCAACCTGAGGCATACGTACCGTCTAC
TGACACTTTTATTGAAAAAGATGCCTCAATCAATGATGAAATTGATCAACTACGACATTCTGCTACAAGTGCATTATTTG
AACGCGATGATGTAATTATTATTGCTAGTGTAAGTTGTATATATGGTTTAGGTAATCCTGAAGAATATAAAGATTTAGTA
GTAAGTGTTCGAGTTGGTATGGAAATGGATAGAAGTGAATTACTTAGAAAACTTGTAGATGTGCAATATACACGAAATGA
CATCGATTTCCAACGAGGAACGTTTCGAGTGCGTGGTGATGTTGTTGAAATATTCCCAGCCTCTAAAGAAGAACTTTGTA
TAAGGGTTGAGTTTTTCGGCGATGAGATTGACCGTATTCGAGAAGTTAACTACCTAACTGGTGAAGTGTTGAAAGAAAGA
GAACATTTTGCGATATTCCCAGCTTCTCACTTCGTAACACGTGAAGAAAAGTTGAAAGTTGCGATTGAACGTATTGAAAA
AGAATTGGAAGAACGATTGAAAGAATTACGAGATGAGAATAAATTACTAGAAGCGCAAAGGTTAGAACAGCGTACCAACT
ATGATTTAGAAATGATGCGAGAGATGGGATTCTGTTCAGGAATTGAAAACTATTCCGTACATTTAACTTTGCGACCACTG
GGTTCGACACCATATACTTTATTGGATTACTTTGGCGATGATTGGTTAGTAATGATTGATGAATCACATGTGACATTACC
GCAAGTTCGAGGCATGTATAACGGAGACAGAGCGCGTAAACAAGTTTTGGTGGATCATGGATTTAGATTACCGAGTGCAT
TAGATAACCGTCCTCTTAAATTTGAAGAATTTGAAGAAAAGACAAAACAACTTGTGTATGTATCTGCAACGCCTGGACCA
TACGAAATTGAACATACGGATAAGATGGTTGAACAAATTATTCGTCCTACTGGTTTACTGGATCCTAAGATTGAGGTTAG
ACCTACTGAAAATCAAATTGACGATTTATTAAGTGAAATTCAAACAAGGGTTGAGCGTAATGAACGCGTACTTGTTACAA
CGCTCACTAAAAAGATGAGTGAAGATTTAACCACATACATGAAAGAAGCGGGTATTAAAGTTAATTATCTGCATTCAGAA
ATCAAGACATTAGAACGAATCGAAATAATTAGAGACTTACGAATGGGTACATATGATGTTATCGTAGGTATTAATTTATT
AAGAGAGGGTATTGATATACCAGAAGTTTCTCTAGTTGTCATATTAGATGCAGATAAAGAAGGATTTTTACGTTCTAACC
GCTCATTAATTCAAACAATAGGTAGAGCTGCGCGTAACGATAAAGGTGAAGTCATTATGTATGCCGATAAAATGACTGAT
TCGATGAAGTATGCAATTGATGAGACACAACGTCGTCGAGAAATACAGATGAAACATAATGAAAAACATGGTATTACACC
TAAAACAATTAATAAAAAAATACATGATTTAATTAGTGCTACTGTTGAAAATGACGAAAATAATGACAAAGCACAAACTG
TGATACCTAAGAAGATGACGAAAAAAGAACGTCAAAAGACAATCGACAATATAGAAAAAGAAATGAAACAAGCAGCGAAA
GATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAAAGCAGAAGGGTGA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (434-546)

• Ultra-violet resistance protein B (UvrB) (553-594)

• Type III restriction enzyme, res subunit (ResIII) (14-140)

• UvrB/uvrC motif (UVR) (626-659)

• UvrB interaction domain (UvrB_inter) (161-251)

3D structure

• AlphaFold DB: A0A0H2XGZ8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	67.534	98.79	0.667
uvrB	Streptococcus pneumoniae TIGR4	67.534	98.79	0.667
uvrB	Streptococcus pneumoniae D39	67.534	98.79	0.667