Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LZG50_RS00150 Genome accession   NZ_CP090611
Coordinates   28548..29138 (+) Length   196 a.a.
NCBI ID   WP_000633669.1    Uniprot ID   B7UME1
Organism   Escherichia coli isolate DCE7     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 23548..34138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LZG50_RS00115 (LZG50_00115) yidG 23840..24202 (+) 363 WP_001113389.1 DUF202 domain-containing protein -
  LZG50_RS00120 (LZG50_00120) yidF 24199..24696 (+) 498 WP_000148036.1 radical SAM protein -
  LZG50_RS00125 (LZG50_00125) emrD 24704..25888 (-) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  LZG50_RS00130 (LZG50_00130) ysdE 25970..26044 (+) 75 WP_211180519.1 protein YsdE -
  LZG50_RS00135 (LZG50_00135) ivbL 26289..26387 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  LZG50_RS00140 (LZG50_00140) ilvB 26493..28181 (+) 1689 WP_000168476.1 acetolactate synthase large subunit -
  LZG50_RS00145 (LZG50_00145) ilvN 28185..28475 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  LZG50_RS00150 (LZG50_00150) letA 28548..29138 (+) 591 WP_000633669.1 transcriptional regulator UhpA Regulator
  LZG50_RS00155 (LZG50_00155) uhpB 29138..30640 (+) 1503 WP_001346621.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  LZG50_RS00160 (LZG50_00160) uhpC 30650..31969 (+) 1320 WP_000936560.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  LZG50_RS00165 (LZG50_00165) uhpT 32107..33498 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20917.32 Da        Isoelectric Point: 5.9982

>NTDB_id=555071 LZG50_RS00150 WP_000633669.1 28548..29138(+) (letA) [Escherichia coli isolate DCE7]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTRRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=555071 LZG50_RS00150 WP_000633669.1 28548..29138(+) (letA) [Escherichia coli isolate DCE7]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCTACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAGACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7UME1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.632

100

0.383