Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   L0F67_RS06990 Genome accession   NZ_CP090556
Coordinates   1415009..1415674 (-) Length   221 a.a.
NCBI ID   WP_014991127.1    Uniprot ID   A0ABT1WXF8
Organism   Actinobacillus suis strain D20_277     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1410009..1420674
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L0F67_RS06975 (L0F67_06960) galT 1410973..1412022 (-) 1050 WP_014991124.1 galactose-1-phosphate uridylyltransferase -
  L0F67_RS06980 (L0F67_06965) - 1412385..1413524 (+) 1140 WP_014991125.1 calcium-binding protein -
  L0F67_RS06985 (L0F67_06970) - 1413637..1415016 (-) 1380 WP_254240668.1 ATP-binding protein -
  L0F67_RS06990 (L0F67_06975) ciaR 1415009..1415674 (-) 666 WP_014991127.1 response regulator Regulator
  L0F67_RS06995 (L0F67_06980) - 1415858..1416217 (-) 360 WP_014991128.1 YgiW/YdeI family stress tolerance OB fold protein -
  L0F67_RS07000 (L0F67_06985) - 1416274..1416642 (-) 369 WP_014991129.1 YgiW/YdeI family stress tolerance OB fold protein -
  L0F67_RS07005 (L0F67_06990) - 1416685..1417068 (-) 384 WP_014991130.1 YgiW/YdeI family stress tolerance OB fold protein -
  L0F67_RS07010 (L0F67_06995) glyA 1417330..1418595 (-) 1266 WP_014991131.1 serine hydroxymethyltransferase -
  L0F67_RS07015 (L0F67_07000) - 1418824..1419711 (-) 888 WP_014991132.1 NAD(+) kinase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25115.94 Da        Isoelectric Point: 6.7304

>NTDB_id=554890 L0F67_RS06990 WP_014991127.1 1415009..1415674(-) (ciaR) [Actinobacillus suis strain D20_277]
MRILLIEDDKLIGDGLKLGLTKQNFVVDWFQDGKLGFDALFSTQYDAVVLDLSLPKMDGLDILKRWRKENQDIPVLILTA
RDTLDDRILGFNSGADDYLCKPFALMEVVVRLQALVRRRYQQSSSEIVIGSLRIDNNTHSVTLAEKAVILTAKEFQLLQL
FVSNKDKVLTRSSIEEKLYSWDNDVGSNTLEVYIHNLRKKLGKSWIKTVHGVGYRLGAEDG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=554890 L0F67_RS06990 WP_014991127.1 1415009..1415674(-) (ciaR) [Actinobacillus suis strain D20_277]
ATGCGTATATTGCTTATTGAAGATGACAAACTCATTGGAGACGGCTTAAAGCTTGGATTGACCAAACAAAATTTTGTGGT
TGATTGGTTTCAAGATGGAAAACTCGGTTTTGATGCGCTGTTCTCCACGCAATACGATGCGGTGGTACTCGATCTCAGCT
TACCGAAAATGGACGGTTTAGACATTTTGAAACGCTGGCGCAAAGAAAATCAAGACATACCGGTGTTAATTCTGACCGCT
CGAGATACGCTCGATGATCGCATTCTTGGCTTTAATTCAGGTGCAGACGATTATCTTTGTAAACCTTTTGCATTAATGGA
AGTGGTTGTGCGCTTACAAGCATTGGTTCGCCGCCGTTATCAACAAAGCTCAAGTGAAATTGTGATTGGCAGTTTACGAA
TTGATAATAATACCCATAGCGTCACGCTAGCGGAAAAAGCGGTCATTTTAACCGCCAAAGAATTTCAGTTATTGCAACTT
TTTGTGAGCAATAAGGATAAGGTGTTAACACGTTCTTCAATCGAGGAAAAATTATATAGCTGGGACAACGATGTCGGCAG
TAACACGCTTGAAGTCTATATCCATAATTTACGTAAGAAACTAGGTAAAAGCTGGATAAAAACCGTCCATGGTGTGGGTT
ATCGTTTAGGAGCTGAAGATGGCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.004

100

0.38
  ciaR Streptococcus pneumoniae D39

37.004

100

0.38
  ciaR Streptococcus pneumoniae R6

37.004

100

0.38
  ciaR Streptococcus pneumoniae TIGR4

37.004

100

0.38
  ciaR Streptococcus mutans UA159

37.557

100

0.376