Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LZ684_RS09675 Genome accession   NZ_CP090456
Coordinates   2035767..2036423 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain B379     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2030767..2041423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LZ684_RS09645 (LZ684_09645) dcyD 2031646..2032632 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  LZ684_RS09650 (LZ684_09650) tcyL 2032647..2033315 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  LZ684_RS09655 (LZ684_09655) tcyN 2033312..2034064 (+) 753 WP_001524857.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LZ684_RS09660 (LZ684_09660) sdiA 2034294..2035016 (+) 723 WP_001619544.1 transcriptional regulator SdiA -
  LZ684_RS09665 (LZ684_09665) yecF 2035084..2035308 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  LZ684_RS09670 (LZ684_09670) yecU 2035295..2035471 (-) 177 WP_001307856.1 protein YecU -
  LZ684_RS09675 (LZ684_09675) letA 2035767..2036423 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LZ684_RS09680 (LZ684_09680) uvrC 2036420..2038252 (+) 1833 WP_001619542.1 excinuclease ABC subunit UvrC Machinery gene
  LZ684_RS09685 (LZ684_09685) pgsA 2038309..2038857 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LZ684_RS09705 (LZ684_09705) yecA 2039506..2040171 (+) 666 WP_001619541.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=554144 LZ684_RS09675 WP_000611328.1 2035767..2036423(+) (letA) [Escherichia coli strain B379]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=554144 LZ684_RS09675 WP_000611328.1 2035767..2036423(+) (letA) [Escherichia coli strain B379]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482