Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   LY257_RS02455 Genome accession   NZ_CP090367
Coordinates   496794..498770 (+) Length   658 a.a.
NCBI ID   WP_001864159.1    Uniprot ID   -
Organism   Helicobacter pylori strain CCUG 17875     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 491794..503770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LY257_RS02440 (LY257_02425) - 493013..493213 (-) 201 WP_151239102.1 hypothetical protein -
  LY257_RS02445 (LY257_02430) - 493182..496058 (+) 2877 Protein_475 DUF3519 domain-containing protein -
  LY257_RS02450 (LY257_02435) - 496062..496753 (+) 692 Protein_476 hypothetical protein -
  LY257_RS02455 (LY257_02440) uvrB 496794..498770 (+) 1977 WP_001864159.1 excinuclease ABC subunit UvrB Machinery gene
  LY257_RS02460 (LY257_02445) - 498781..499614 (-) 834 WP_000816963.1 outer membrane protein -
  LY257_RS02465 (LY257_02450) purB 499679..501001 (-) 1323 WP_000893913.1 adenylosuccinate lyase -
  LY257_RS02470 (LY257_02455) - 501111..502055 (-) 945 WP_000238149.1 thiamine pyrophosphate-dependent enzyme -
  LY257_RS02475 (LY257_02460) - 502068..503291 (-) 1224 WP_000124351.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  LY257_RS02480 (LY257_02465) - 503301..503693 (-) 393 WP_000656174.1 4Fe-4S dicluster-binding protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 76018.47 Da        Isoelectric Point: 6.7308

>NTDB_id=553718 LY257_RS02455 WP_001864159.1 496794..498770(+) (uvrB) [Helicobacter pylori strain CCUG 17875]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQTNKPALIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISTTGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEVTSYRRTKQEEFNKIHNITPKTVTRALEEELKLRDDEIRIAKALKKDKMPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAQLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=553718 LY257_RS02455 WP_001864159.1 496794..498770(+) (uvrB) [Helicobacter pylori strain CCUG 17875]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGAAGCGGTAAGACTTATACGATGGCCAATATCATCGCTC
AAACCAATAAACCCGCTTTGATCATGAGCCATAATAAAACCTTATGTGCACAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGACCACCTCACTTTTAGGTTATGATG
ATGTGATTGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGCAACCCTGAAGAATATTTGAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTATAAGAGCTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGAGGGAGCTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCGGTCTTTGACGCTTTAGAAAGAAATGAGATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGCCAGTTTGCCGTAGGGAGCGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TCTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCACGACCGGTGTGTGTAAGGGCATTGAAAATTACGCACGCCATTTTACAGGCAAAGCCCCCAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATTTTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCCAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTCATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAGGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAATCATATTATCCGCTCTTTGAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGCG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTACTATACGCTAAAAAGATCACC
CAAAGCATGCAAAAAGCCTTTGAAGTTACTAGCTACAGGCGCACTAAGCAAGAAGAGTTTAATAAAATTCATAATATCAC
CCCTAAAACCGTTACTCGTGCTTTAGAAGAGGAATTGAAATTAAGAGACGATGAGATTAGAATCGCTAAAGCCTTAAAAA
AGGACAAAATGCCTAAAAGTGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTCAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(623-657)

Type III restriction enzyme, res subunit (ResIII)

(15-137)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB interaction domain (UvrB_inter)

(159-248)

Ultra-violet resistance protein B (UvrB)

(554-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.472

100

0.498
  uvrB Streptococcus pneumoniae TIGR4

49.472

100

0.498
  uvrB Streptococcus pneumoniae D39

49.472

100

0.498