Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LXF06_RS04855 Genome accession   NZ_CP090305
Coordinates   1026278..1026868 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain Z503     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1021278..1031868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXF06_RS04820 yidF 1021394..1021891 (+) 498 WP_000148061.1 radical SAM protein -
  LXF06_RS04825 emrD 1021899..1023082 (-) 1184 Protein_927 multidrug efflux MFS transporter EmrD -
  LXF06_RS04830 ysdE 1023164..1023238 (+) 75 WP_211180519.1 protein YsdE -
  LXF06_RS04835 tisB 1023362..1023451 (-) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  LXF06_RS04840 ivbL 1024016..1024114 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  LXF06_RS04845 ilvB 1024220..1025908 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  LXF06_RS04850 ilvN 1025912..1026202 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  LXF06_RS04855 letA 1026278..1026868 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  LXF06_RS04860 uhpB 1026868..1028370 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  LXF06_RS04865 uhpC 1028380..1029699 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  LXF06_RS04870 uhpT 1029837..1031228 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=553492 LXF06_RS04855 WP_000633668.1 1026278..1026868(+) (letA) [Escherichia coli strain Z503]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=553492 LXF06_RS04855 WP_000633668.1 1026278..1026868(+) (letA) [Escherichia coli strain Z503]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378