Detailed information NTG0553216

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: J7U24_RS03225
• Genome accession: NZ_CP072440
• Coordinates: 610131..611132 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain S24730
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 605131..616132

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U24_RS03205 (J7U24_03210)	smpB	606238..606702 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
J7U24_RS03210 (J7U24_03215)	-	606856..608262 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
J7U24_RS03215 (J7U24_03220)	-	608264..608629 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
J7U24_RS03220 (J7U24_03225)	-	608732..609817 (-)	1086	WP_011680935.1	Xaa-Pro peptidase family protein	-
J7U24_RS03225 (J7U24_03230)	ccpA	610131..611132 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
J7U24_RS03230 (J7U24_03235)	-	611191..611388 (+)	198	WP_014608125.1	hypothetical protein	-
J7U24_RS03235	-	611494..611718 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
J7U24_RS03240 (J7U24_03240)	-	611719..612258 (+)	540	WP_011680936.1	MmcQ/YjbR family DNA-binding protein	-
J7U24_RS03245 (J7U24_03245)	-	612271..613386 (+)	1116	WP_011680937.1	glycerate kinase	-
J7U24_RS03250 (J7U24_03250)	-	613433..613888 (-)	456	WP_011680938.1	YueI family protein	-
J7U24_RS03255 (J7U24_03255)	eno	614097..615401 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=553216 J7U24_RS03225 WP_004197422.1 610131..611132(+) (ccpA) [Streptococcus thermophilus strain S24730]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=553216 J7U24_RS03225 WP_004197422.1 610131..611132(+) (ccpA) [Streptococcus thermophilus strain S24730]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547