Detailed information NTG0552918

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: J7U23_RS03220
• Genome accession: NZ_CP072435
• Coordinates: 597505..598506 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain S24736
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 592505..603506

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U23_RS03200 (J7U23_03190)	smpB	593612..594076 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
J7U23_RS03205 (J7U23_03195)	-	594230..595636 (+)	1407	WP_082308872.1	Cof-type HAD-IIB family hydrolase	-
J7U23_RS03210 (J7U23_03200)	-	595638..596003 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
J7U23_RS03215 (J7U23_03205)	-	596106..597191 (-)	1086	WP_011225703.1	Xaa-Pro peptidase family protein	-
J7U23_RS03220 (J7U23_03210)	ccpA	597505..598506 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
J7U23_RS03225 (J7U23_03215)	-	598565..598762 (+)	198	WP_014608125.1	hypothetical protein	-
J7U23_RS03230 (J7U23_03220)	-	598868..599632 (+)	765	WP_116920163.1	MmcQ/YjbR family DNA-binding protein	-
J7U23_RS03235 (J7U23_03225)	-	599645..600760 (+)	1116	WP_116920164.1	glycerate kinase	-
J7U23_RS03240 (J7U23_03230)	-	600799..601254 (-)	456	WP_087009787.1	YueI family protein	-
J7U23_RS03245 (J7U23_03235)	eno	601462..602766 (+)	1305	WP_116920165.1	surface-displayed alpha-enolase	-
J7U23_RS03250 (J7U23_03240)	-	602919..603103 (-)	185	Protein_578	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=552918 J7U23_RS03220 WP_004197422.1 597505..598506(+) (ccpA) [Streptococcus thermophilus strain S24736]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=552918 J7U23_RS03220 WP_004197422.1 597505..598506(+) (ccpA) [Streptococcus thermophilus strain S24736]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCTCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGATGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547