Detailed information NTG0552860

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: J7T96_RS03335
• Genome accession: NZ_CP072434
• Coordinates: 618201..619202 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain S24742
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 613201..624202

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T96_RS03315 (J7T96_03250)	smpB	614308..614772 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
J7T96_RS03320 (J7T96_03255)	-	614926..616332 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
J7T96_RS03325 (J7T96_03260)	-	616334..616699 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
J7T96_RS03330 (J7T96_03265)	-	616802..617887 (-)	1086	WP_011680935.1	Xaa-Pro peptidase family protein	-
J7T96_RS03335 (J7T96_03270)	ccpA	618201..619202 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
J7T96_RS03340 (J7T96_03275)	-	619261..619458 (+)	198	WP_014608125.1	hypothetical protein	-
J7T96_RS03345	-	619564..619788 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
J7T96_RS03350 (J7T96_03280)	-	619789..620328 (+)	540	WP_011680936.1	MmcQ/YjbR family DNA-binding protein	-
J7T96_RS03355 (J7T96_03285)	-	620341..621456 (+)	1116	WP_011680937.1	glycerate kinase	-
J7T96_RS03360 (J7T96_03290)	-	621503..621958 (-)	456	WP_011680938.1	YueI family protein	-
J7T96_RS03365 (J7T96_03295)	eno	622167..623471 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
J7T96_RS03370 (J7T96_03300)	-	623623..623808 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=552860 J7T96_RS03335 WP_004197422.1 618201..619202(+) (ccpA) [Streptococcus thermophilus strain S24742]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=552860 J7T96_RS03335 WP_004197422.1 618201..619202(+) (ccpA) [Streptococcus thermophilus strain S24742]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547