Detailed information NTG0552846

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: J7T96_RS01530
• Genome accession: NZ_CP072434
• Coordinates: 277176..278075 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain S24742
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 272176..283075

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T96_RS01510 (J7T96_01485)	trkA	273312..274661 (-)	1350	WP_207559738.1	Trk system potassium transporter TrkA	-
J7T96_RS01515 (J7T96_01490)	-	274950..275459 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
J7T96_RS01520 (J7T96_01495)	-	275771..276328 (+)	558	WP_002949523.1	ECF transporter S component	-
J7T96_RS01525 (J7T96_01500)	-	276331..276981 (+)	651	WP_011225447.1	phosphatase PAP2 family protein	-
J7T96_RS01530 (J7T96_01505)	comR	277176..278075 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
J7T96_RS01535	-	278313..278744 (+)	432	Protein_250	cysteine peptidase family C39 domain-containing protein	-
J7T96_RS01540	-	278774..279490 (+)	717	Protein_251	ABC transporter transmembrane domain-containing protein	-
J7T96_RS01545	comA	279512..280345 (+)	834	WP_269149495.1	ATP-binding cassette domain-containing protein	Regulator
J7T96_RS01550 (J7T96_01515)	-	280453..280770 (+)	318	WP_179970762.1	DUF805 domain-containing protein	-
J7T96_RS01555	-	280986..281333 (-)	348	WP_232085744.1	DUF4153 domain-containing protein	-
J7T96_RS01560	-	281258..281878 (-)	621	WP_232085704.1	DUF4153 domain-containing protein	-
J7T96_RS01565 (J7T96_01525)	-	282559..283074 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=552846 J7T96_RS01530 WP_014607953.1 277176..278075(+) (comR) [Streptococcus thermophilus strain S24742]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=552846 J7T96_RS01530 WP_014607953.1 277176..278075(+) (comR) [Streptococcus thermophilus strain S24742]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418