Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   J7U07_RS01640 Genome accession   NZ_CP072433
Coordinates   297607..299124 (+) Length   505 a.a.
NCBI ID   WP_207559739.1    Uniprot ID   A0A3G6JL13
Organism   Streptococcus thermophilus strain S24743     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 292607..304124
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U07_RS01610 - 292887..293057 (+) 171 Protein_264 ascorbate 6-phosphate lactonase -
  J7U07_RS01615 (J7U07_01590) - 293074..293745 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  J7U07_RS01620 (J7U07_01595) - 293785..295149 (-) 1365 WP_269149496.1 TrkH family potassium uptake protein -
  J7U07_RS01625 (J7U07_01600) rsmG 295219..295932 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  J7U07_RS01630 (J7U07_01605) - 296229..296765 (+) 537 WP_002946488.1 DUF177 domain-containing protein -
  J7U07_RS01635 (J7U07_01610) covR 296921..297610 (+) 690 WP_002949638.1 response regulator transcription factor Regulator
  J7U07_RS01640 (J7U07_01615) covS 297607..299124 (+) 1518 WP_207559739.1 HAMP domain-containing histidine kinase Regulator
  J7U07_RS01645 (J7U07_01620) nrdR 299246..299725 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  J7U07_RS01650 (J7U07_01625) - 299722..300897 (+) 1176 WP_002949643.1 DnaD domain protein -
  J7U07_RS01655 (J7U07_01630) dnaI 300901..301803 (+) 903 WP_002946786.1 primosomal protein DnaI -
  J7U07_RS01660 (J7U07_01635) der 301909..303219 (+) 1311 WP_014607972.1 ribosome biogenesis GTPase Der -
  J7U07_RS01665 (J7U07_01640) - 303283..303942 (+) 660 Protein_275 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57557.99 Da        Isoelectric Point: 5.5179

>NTDB_id=552790 J7U07_RS01640 WP_207559739.1 297607..299124(+) (covS) [Streptococcus thermophilus strain S24743]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSSEPLLAAFY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLKFYYALKERLIFLLIFLEVGMTVLVIAVIVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=552790 J7U07_RS01640 WP_207559739.1 297607..299124(+) (covS) [Streptococcus thermophilus strain S24743]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTTCAGAGCCGCTTTTAGCGGCCTTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGAAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAATTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACAATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

ArlS sensor domain (ArlS_N)

(39-187)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3G6JL13

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.024

99.406

0.935