Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   J7T92_RS05450 Genome accession   NZ_CP072429
Coordinates   1026883..1028223 (-) Length   446 a.a.
NCBI ID   WP_372588877.1    Uniprot ID   A0A3G6JJJ9
Organism   Streptococcus thermophilus strain S24747     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1021883..1033223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T92_RS05420 (J7T92_05420) - 1022003..1022389 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  J7T92_RS05425 (J7T92_05425) - 1022481..1023359 (-) 879 Protein_1013 GNAT family N-acetyltransferase -
  J7T92_RS05430 (J7T92_05430) yidA 1023567..1024376 (+) 810 WP_011226081.1 sugar-phosphatase -
  J7T92_RS05435 (J7T92_05435) - 1024378..1025592 (+) 1215 WP_002953123.1 aminoacyltransferase -
  J7T92_RS05440 (J7T92_05440) - 1025644..1026005 (-) 362 Protein_1016 YbaN family protein -
  J7T92_RS05445 (J7T92_05445) vicX 1026065..1026877 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  J7T92_RS05450 (J7T92_05450) vicK 1026883..1028223 (-) 1341 WP_372588877.1 cell wall metabolism sensor histidine kinase VicK Regulator
  J7T92_RS05455 (J7T92_05455) vicR 1028216..1028923 (-) 708 WP_011681206.1 response regulator YycF Regulator
  J7T92_RS05460 (J7T92_05460) - 1029450..1030217 (+) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  J7T92_RS05465 (J7T92_05465) - 1030229..1031062 (+) 834 WP_011681208.1 transporter substrate-binding domain-containing protein -
  J7T92_RS05470 (J7T92_05470) - 1031080..1031778 (+) 699 WP_011681209.1 amino acid ABC transporter permease -
  J7T92_RS05475 (J7T92_05475) - 1031790..1032440 (+) 651 WP_011226088.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50738.03 Da        Isoelectric Point: 5.2464

>NTDB_id=552640 J7T92_RS05450 WP_372588877.1 1026883..1028223(-) (vicK) [Streptococcus thermophilus strain S24747]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLRIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALICKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=552640 J7T92_RS05450 WP_372588877.1 1026883..1028223(-) (vicK) [Streptococcus thermophilus strain S24747]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTTCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTTGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

HAMP domain (HAMP)

(37-79)

PAS fold (PAS)

(94-180)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3G6JJJ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.155

92.825

0.688
  micB Streptococcus pneumoniae Cp1015

65.82

97.085

0.639