Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   LXA46_RS00880 Genome accession   NZ_CP089948
Coordinates   177137..179968 (+) Length   943 a.a.
NCBI ID   WP_001152899.1    Uniprot ID   P63384
Organism   Streptococcus pneumoniae TIGR4     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 172137..184968
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA46_RS00855 (LXA46_00850) - 172706..173269 (+) 564 WP_000166604.1 DNA-3-methyladenine glycosylase I -
  LXA46_RS00860 (LXA46_00855) - 173266..173943 (+) 678 WP_000987408.1 type II CAAX endopeptidase family protein -
  LXA46_RS00865 (LXA46_00860) - 174080..175111 (-) 1032 WP_000255096.1 S66 peptidase family protein -
  LXA46_RS00870 (LXA46_00865) - 175366..176049 (-) 684 WP_000078022.1 DUF1129 domain-containing protein -
  LXA46_RS00875 (LXA46_00870) - 176061..177005 (-) 945 WP_000815629.1 magnesium transporter CorA family protein -
  LXA46_RS00880 (LXA46_00875) uvrA 177137..179968 (+) 2832 WP_001152899.1 excinuclease ABC subunit UvrA Machinery gene
  LXA46_RS00885 (LXA46_00880) - 179961..181022 (+) 1062 WP_001042856.1 Xaa-Pro peptidase family protein -
  LXA46_RS00890 (LXA46_00885) spx 181154..181552 (+) 399 WP_000591165.1 transcriptional regulator Spx -
  LXA46_RS00895 (LXA46_00890) - 181618..182187 (+) 570 WP_000725133.1 SP0191 family lipoprotein -
  LXA46_RS00900 (LXA46_00895) - 182274..182540 (+) 267 WP_000507059.1 IreB family regulatory phosphoprotein -
  LXA46_RS00905 (LXA46_00900) ruvX 182544..182963 (+) 420 WP_001808830.1 Holliday junction resolvase RuvX -
  LXA46_RS00910 (LXA46_00905) - 182979..183284 (+) 306 WP_000017620.1 DUF1292 domain-containing protein -
  LXA46_RS00915 (LXA46_00910) - 183543..184793 (+) 1251 WP_000464332.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -

Sequence

Protein


Download         Length: 943 a.a.        Molecular weight: 104185.31 Da        Isoelectric Point: 6.3544

>NTDB_id=552641 LXA46_RS00880 WP_001152899.1 177137..179968(+) (uvrA) [Streptococcus pneumoniae TIGR4]
MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGL
SPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDD
SELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNML
EQAMKVFGVAMDKPFEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYTRTQMRLYM
NELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLI
DVGPGAGVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNLQNVTARFPLGKFIAVT
GVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVEFF
QHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIARLLKVLARFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIVTGTPEEVAANEASYTGHYLKGKLHHE

Nucleotide


Download         Length: 2832 bp        

>NTDB_id=552641 LXA46_RS00880 WP_001152899.1 177137..179968(+) (uvrA) [Streptococcus pneumoniae TIGR4]
ATGCAAGATAAAATTGTCATTCATGGGGCGCGTGCCCATAATTTAAAAAATATTGATGTGGAGATTCCGCGAGACAAGTT
GGTTGTCGTGACTGGCTTGTCAGGTTCAGGGAAGTCCAGTCTGGCTTTTGATACTCTCTATGCGGAGGGACAACGTCGCT
ATGTAGAGAGTTTGTCCGCCTACGCTCGTCAGTTCTTGGGAAATATGGAAAAACCAGATGTAGATGCCATTGATGGTCTC
AGCCCAGCTATTTCCATCGACCAGAAAACGACTAGTAAAAATCCTCGCTCGACGGTGGGAACGACGACTGAAATCAATGA
CTATCTGCGTCTCCTCTACGCACGTGTGGGGACGCCTTACTGTATCAACGGACATGGAGCTATCAATGCTTCTTCTGTGG
AGCAAATCGTTGATAAGGTTTTGGAGTTACCTGAACGCCAGCGCTTGCAGATCTTGGCTCCTGTCATCCGCAAGAAAAAA
GGCCAACATAAGAGTGTTATCGAGAAGGTTCAGAAAGACGGGTATGTTCGTGTCCGTGTGGATGGGGAAGTCTATGATGT
GACCGAAGTGCCAGAGTTGTCTAAGAGCAAGCAACACAATATCGATGTCGTGGTTGACCGTATTGTTATCAAGGAGGGCA
TTCGTAGTCGTCTCTTTGATTCCATTGAGGCTGCCCTTCGTATTGCAGAAGGTTATGTCATTATCGACACCATGGACGAC
TCGGAGTTGTTGTTCTCTGAGCATTATGCCTGTCCAGTTTGTGGTTTTACTGTCCCAGAGTTAGAGCCTCGTCTCTTTTC
TTTCAATGCTCCTTTTGGCTCTTGTAGTGAGTGTGACGGCTTGGGCATCAAGCTGGAGGTGGATACTGATTTGGTAGTGC
CAGATGCTAGCAAAACCTTACGTGAGGGAGCGCTAGCACCTTGGAATCCTATCTCATCCAACTACTATCCAAACATGTTA
GAGCAGGCCATGAAAGTCTTTGGAGTGGCTATGGATAAGCCTTTTGAGGACCTGTCAGAAGAAGATAAGAACTTGATTCT
CTATGGGTCAGATGGTAAGGAATTCCATTTCCACTATGAGAATGAATTTGGTGGCGTGCGCGATATCGACATTCCGTTTG
AGGGAGTTATCAATAATATCAAACGTCGTTACCATGAAACCAATAGCGATTACACTCGCACTCAGATGCGTCTCTACATG
AATGAGCTGACCTGCGGAACCTGTCAAGGCTATCGTCTCAATGACCAGGCCTTGTCTGTCCGTGTGGGCGGCCAGCAAGG
GCCACATATTGGAGAAATCTCAGACCTGTCTATCGCTGACCACTTGGACTTGGTGAGCCAGTTAACTTTGTCTGAAAATG
AAGCCATCATTGCTCGTCCCATTCTCAAGGAAATCAAGGATCGTTTGACCTTCCTTAATAATGTGGGTCTTAACTATCTA
ACCCTGTCACGTTCAGCAGGAACCCTTTCAGGTGGGGAAAGTCAGCGCATTCGTTTGGCAACCCAGATTGGTTCCAACCT
ATCAGGTGTCCTCTATATCCTAGACGAGCCGTCAATCGGTCTTCACCAGAGGGACAATGATCGCCTGATTGCCAGTCTGA
AAAAGATGCGTGACTTGGGCAATACTCTTATCGTGGTGGAACACGACGAAGATACCATGCGTGAGGCTGATTATCTGATT
GACGTTGGTCCTGGTGCCGGTGTTTTTGGTGGTGAGATTGTTGCAGCAGGTACACCTAAGCAAGTGGCTCGCAACAGCAA
GTCTATCACAGGTCAGTACTTGTCAGGCAAACGTGTCATCCCAGTACCAGAAGAGCGCCGTGTCGGAAATGGTCGTTTTA
TTGAAGTGATAGGAGCGCGTGAGAACAACTTGCAAAATGTCACGGCTCGCTTTCCACTAGGAAAATTTATCGCAGTGACA
GGTGTGTCGGGTTCAGGGAAATCGACTCTAATCAACAGCATTCTCAAAAAAGCCATTGCCCAGAAGCTCAACCGTAATTC
AGACAAACCTGGTAAGTTTAAGACTATTACAGGGATTGAGCATGTCGACCGTTTGATTGATATTGACCAGAGCCCTATCG
GACGGACGCCGAGGTCTAACCCAGCTACCTATACAGGAGTTTTTGACGATATACGTGACCTTTTTGCTCAGACAAATGAA
GCCAAGATTCGAGGCTACAAGAAGGGGCGCTTCAGTTTCAACGTCAAGGGAGGTCGCTGTGAAGCTTGCTCAGGTGACGG
GATTATCAAGATTGAGATGCACTTCTTGCCAGATGTTTATGTGGCTTGTGAAGTTTGCCACGGAACCCGCTATAACAGTG
AAACCCTAGAAGTTCACTACAAGGAAAAGAATATTTCGCAGGTCTTGGATATGACGGTCAACGATGCGGTAGAATTTTTC
CAACACATTCCGAAAATTCAACGCAAACTCCAGACCATCAAGGATGTAGGGCTAGGCTATGTGACCTTGGGACAGCCAGC
TACCACCCTTTCTGGGGGAGAAGCCCAACGTATGAAGTTAGCTAGCGAACTCCACAAACGATCGACAGGAAAATCTTTCT
ACATTCTGGATGAGCCGACGACAGGGCTTCATACAGAGGACATTGCTCGCCTGCTCAAGGTTTTAGCTCGCTTTGTAGAC
GATGGCAATACAGTCCTCGTCATCGAGCACAATCTGGATGTTATCAAGACGGCAGACCATATCATTGACTTGGGACCTGA
GGGCGGTGTCGGTGGTGGAACCATCATCGTAACAGGAACTCCAGAAGAAGTAGCTGCCAACGAAGCCAGCTATACAGGAC
ACTATTTGAAAGGAAAGTTACATCATGAATAA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(132-238)

ABC transporter (ABC_tran)

(624-860)

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63384

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

100

100

1
  uvrA Streptococcus pneumoniae TIGR4

100

100

1
  uvrA Streptococcus pneumoniae D39

100

100

1