Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   HP1CH_RS05720 Genome accession   NZ_AP013355
Coordinates   1175268..1177244 (-) Length   658 a.a.
NCBI ID   WP_001127890.1    Uniprot ID   P94846
Organism   Helicobacter pylori 26695-1CH     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1170268..1182244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HP1CH_RS05695 - 1170344..1170736 (+) 393 WP_000656174.1 4Fe-4S dicluster-binding protein -
  HP1CH_RS05700 - 1170746..1171969 (+) 1224 WP_001129867.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  HP1CH_RS05705 - 1171982..1172926 (+) 945 WP_000238135.1 thiamine pyrophosphate-dependent enzyme -
  HP1CH_RS05710 purB 1173036..1174358 (+) 1323 WP_000893828.1 adenylosuccinate lyase -
  HP1CH_RS05715 - 1174424..1175257 (+) 834 WP_000816949.1 outer membrane protein -
  HP1CH_RS05720 uvrB 1175268..1177244 (-) 1977 WP_001127890.1 excinuclease ABC subunit UvrB Machinery gene
  HP1CH_RS05725 - 1177285..1177997 (-) 713 Protein_1078 hypothetical protein -
  HP1CH_RS05730 - 1178014..1180887 (-) 2874 WP_000775280.1 DUF3519 domain-containing protein -
  HP1CH_RS09110 - 1180856..1181056 (+) 201 Protein_1080 hypothetical protein -
  HP1CH_RS05735 - 1181297..1182067 (-) 771 WP_000540113.1 HP1117 family Sel1-like repeat protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75916.42 Da        Isoelectric Point: 6.8804

>NTDB_id=55240 HP1CH_RS05720 WP_001127890.1 1175268..1177244(-) (uvrB) [Helicobacter pylori 26695-1CH]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQTNKPALIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALEKNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARGERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKIHNITPKTVTRALEEELKLRDDEIRIAKALKKDKMPKSEREKIIKELDKKMRECTKNL
DFEEAMRLRDEIAQLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=55240 HP1CH_RS05720 WP_001127890.1 1175268..1177244(-) (uvrB) [Helicobacter pylori 26695-1CH]
ATGCCCTTATTTGATTTAAAAAGCCCTTATCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTGACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGAAGCGGTAAGACTTATACGATGGCCAATATCATCGCTC
AAACCAATAAACCCGCTTTGATCATGAGCCATAATAAGACCTTATGCGCACAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGGAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGACCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTACAAGAGTTTTTTATTAAAGCTAGTGGAAATGGGCTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTTAGAGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCGGTCTTTGACGCTTTAGAAAAAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGCGAGAGGCTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGGTTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCGACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTCACCGGTAAAGCCCCTAACGAAACG
CCTTTTTGCTTGTTTGATTATTTAGGGATTTTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
ACAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGTGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCCAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTGTTTGATGAAATCAAGTTAGTGGTGGCTAGAGGTGAAAGGGTGCTCATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAGGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAGATCACT
CAAAGCATGCAAAAAGCCTTTGAGATCACTAGTTACAGGCGCGCCAAACAAGAAGAGTTCAATAAAATCCATAACATCAC
CCCCAAAACCGTTACGCGCGCTTTAGAAGAGGAATTGAAATTAAGAGACGATGAAATTAGAATCGCTAAAGCCTTAAAAA
AGGACAAAATGCCTAAAAGTGAAAGGGAAAAAATCATTAAAGAATTGGATAAAAAAATGCGAGAATGCACGAAGAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTCAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(554-595)

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

Type III restriction enzyme, res subunit (ResIII)

(15-137)

UvrB interaction domain (UvrB_inter)

(159-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P94846

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.472

100

0.498
  uvrB Streptococcus pneumoniae D39

49.472

100

0.498
  uvrB Streptococcus pneumoniae TIGR4

49.472

100

0.498

Multiple sequence alignment