Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   LUZ00_RS03975 Genome accession   NZ_CP089498
Coordinates   820047..822032 (+) Length   661 a.a.
NCBI ID   WP_000229253.1    Uniprot ID   A0A0H2XGZ8
Organism   Staphylococcus aureus strain M03/0073_III_ST239     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 815047..827032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ00_RS03945 - 816090..816194 (+) 105 WP_001790092.1 hypothetical protein -
  LUZ00_RS03950 prfB 816363..817473 (+) 1111 WP_010956549.1 peptide chain release factor 2 -
  LUZ00_RS03955 - 817627..817734 (+) 108 WP_001790093.1 hypothetical protein -
  LUZ00_RS03960 - 817882..818721 (+) 840 WP_000749380.1 CHAP domain-containing protein -
  LUZ00_RS03965 - 818895..819545 (+) 651 WP_000538141.1 YfbR-like 5'-deoxynucleotidase -
  LUZ00_RS03970 - 819542..819778 (+) 237 WP_000638419.1 CsbA family protein -
  LUZ00_RS03975 uvrB 820047..822032 (+) 1986 WP_000229253.1 excinuclease ABC subunit UvrB Machinery gene
  LUZ00_RS03980 uvrA 822040..824886 (+) 2847 WP_000662681.1 excinuclease ABC subunit UvrA Machinery gene
  LUZ00_RS03985 hprK 825493..826425 (+) 933 WP_000958224.1 HPr(Ser) kinase/phosphatase -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 76648.34 Da        Isoelectric Point: 5.0538

>NTDB_id=551370 LUZ00_RS03975 WP_000229253.1 820047..822032(+) (uvrB) [Staphylococcus aureus strain M03/0073_III_ST239]
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFK
EFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKER
EHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPL
GSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGP
YEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSE
IKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTD
SMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAK
DLDFEKATELRDMLFELKAEG

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=551370 LUZ00_RS03975 WP_000229253.1 820047..822032(+) (uvrB) [Staphylococcus aureus strain M03/0073_III_ST239]
ATGGTTGAACATTATCCTTTTAAAATACATTCTGATTTTGAGCCTCAAGGTGACCAACCGCAAGCAATTAAAGAAATCGT
GGAAGGTATTAAAGCGGGGAAAAGACATCAAACTTTATTAGGTGCTACTGGCACAGGGAAAACATTTACGATGAGTAATG
TTATTAAAGAAGTTGGGAAACCAACGTTAATTATCGCGCATAACAAAACATTAGCAGGACAATTATATAGTGAGTTTAAA
GAATTTTTTCCTGAAAACAGGGTGGAATACTTTGTAAGTTACTATGATTATTATCAACCAGAGGCATACGTACCGTCTAC
TGACACTTTTATTGAAAAAGATGCCTCAATCAATGATGAAATTGATCAACTACGACATTCTGCTACAAGTGCATTATTTG
AACGCGATGATGTAATTATTATTGCTAGTGTAAGTTGTATATATGGTTTAGGTAATCCTGAAGAATATAAAGATTTAGTA
GTAAGTGTTCGAGTTGGTATGGAAATGGATAGAAGTGAATTACTTAGAAAACTTGTAGATGTGCAATATACACGAAATGA
CATCGATTTCCAACGAGGAACGTTTCGAGTGCGTGGTGATGTAGTGGAAATATTCCCAGCCTCTAAAGAAGAACTTTGTA
TAAGGGTTGAGTTTTTCGGCGATGAGATTGACCGTATCCGAGAAGTTAACTACCTAACAGGTGAAGTGTTGAAAGAAAGA
GAACATTTTGCGATATTCCCAGCTTCTCACTTCGTAACACGTGAAGAAAAGTTGAAAGTTGCGATTGAACGTATTGAAAA
AGAATTGGAAGAACGATTGAAAGAATTACGAGATGAGAATAAATTACTAGAAGCGCAAAGGTTAGAACAGCGTACCAACT
ATGATTTAGAAATGATGCGAGAGATGGGATTCTGTTCAGGAATTGAAAACTATTCCGTACATTTAACTTTGCGACCACTG
GGTTCGACACCATATACTTTATTGGATTACTTTGGCGATGATTGGTTAGTAATGATTGATGAATCACATGTGACATTACC
GCAAGTTCGAGGCATGTATAACGGAGACAGAGCGCGTAAACAAGTTTTGGTGGATCATGGGTTTAGATTACCGAGTGCAT
TAGATAACCGTCCACTTAAATTTGAAGAATTTGAAGAAAAGACAAAACAACTTGTGTATGTATCTGCAACGCCTGGACCA
TACGAAATTGAACATACGGATAAGATGGTTGAACAAATTATTCGTCCTACTGGTTTACTGGATCCTAAGATTGAGGTTAG
ACCTACTGAAAATCAAATTGACGATTTATTAAGTGAAATTCAAACAAGAGTTGAGCGTAATGAACGCGTACTTGTTACAA
CGCTCACTAAAAAGATGAGTGAAGATTTAACCACATACATGAAAGAAGCGGGTATTAAAGTTAATTATCTGCATTCAGAA
ATCAAGACATTAGAACGAATTGAAATAATTAGAGACTTACGAATGGGTACATATGATGTTATCGTAGGTATTAATTTATT
AAGAGAGGGTATTGATATACCAGAAGTTTCTCTAGTTGTCATATTAGATGCAGATAAAGAAGGGTTTTTACGTTCTAACC
GCTCATTAATTCAAACAATAGGTAGAGCTGCGCGTAACGATAAAGGTGAAGTCATTATGTATGCCGATAAAATGACTGAT
TCGATGAAGTATGCAATTGATGAGACACAACGTCGTCGAGAAATACAGATGAAACATAATGAAAAACATGGTATTACACC
TAAAACAATTAATAAAAAAATACATGATTTAATTAGTGCTACTGTTGAAAATGACGAAAATAATGACAAAGCACAAACTG
TGATACCTAAGAAGATGACGAAAAAAGAACGTCAAAAGACAATCGACAATATAGAAAAAGAAATGAAACAAGCAGCGAAA
GATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAAAGCAGAAGGGTGA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(434-546)

Ultra-violet resistance protein B (UvrB)

(553-594)

Type III restriction enzyme, res subunit (ResIII)

(14-140)

UvrB/uvrC motif (UVR)

(626-659)

UvrB interaction domain (UvrB_inter)

(161-251)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XGZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

67.534

98.79

0.667
  uvrB Streptococcus pneumoniae TIGR4

67.534

98.79

0.667
  uvrB Streptococcus pneumoniae D39

67.534

98.79

0.667