Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   J5Z97_RS05125 Genome accession   NZ_CP072112
Coordinates   1005486..1006796 (-) Length   436 a.a.
NCBI ID   WP_023611413.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M08500     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1000486..1011796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5Z97_RS05100 (J5Z97_05100) - 1001093..1002145 (-) 1053 WP_002989701.1 BMP family protein -
  J5Z97_RS05105 (J5Z97_05105) - 1002239..1002628 (-) 390 WP_002984531.1 cytidine deaminase -
  J5Z97_RS05110 (J5Z97_05110) - 1003279..1003872 (-) 594 WP_002989699.1 class I SAM-dependent methyltransferase -
  J5Z97_RS05115 (J5Z97_05115) coaA 1004140..1005060 (+) 921 WP_010922353.1 type I pantothenate kinase -
  J5Z97_RS05120 (J5Z97_05120) rpsT 1005114..1005362 (+) 249 WP_168390202.1 30S ribosomal protein S20 -
  J5Z97_RS05125 (J5Z97_05125) ciaH 1005486..1006796 (-) 1311 WP_023611413.1 HAMP domain-containing sensor histidine kinase Regulator
  J5Z97_RS05130 (J5Z97_05130) ciaR 1006789..1007463 (-) 675 WP_002984519.1 response regulator transcription factor Regulator
  J5Z97_RS05135 (J5Z97_05135) - 1007810..1010347 (-) 2538 WP_023611410.1 M1 family metallopeptidase -
  J5Z97_RS05140 (J5Z97_05140) phoU 1010552..1011205 (-) 654 WP_002984514.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 50096.66 Da        Isoelectric Point: 9.2899

>NTDB_id=550481 J5Z97_RS05125 WP_023611413.1 1005486..1006796(-) (ciaH) [Streptococcus pyogenes strain M08500]
MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYFDTENNII
KALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKRRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
PAVAFMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQN
QVNRSLRMDKALLKQLITILFDNAIKYTDKNGIIEIIVKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=550481 J5Z97_RS05125 WP_023611413.1 1005486..1006796(-) (ciaH) [Streptococcus pyogenes strain M08500]
ATGAATAAATTAAAAAAAGAGATTTTATCAGATAACTATAACCACTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTCATTATGACTATTATTATCTTACAGATTATGCGGTTTGGCGTTTATTCGTCAGTTGACAGTAGTTTAGTTTCTGTTA
GTAATAATGCAAGTAGCTATGCTAATCGTACGATGGCTAGAATATCTTCTTTTTACTTTGATACTGAAAATAACATTATT
AAGGCGCTGCCTGATTCAGATAGTTCTAAGTTATTAGGAACGCCTGCAGCTAATACAGATATCATTTTGTTTAGTGCTAA
TGGAACAATTTTAAATGCTTTTGATGCGTTTTCTAACTATCAAAATTTTCATTTAGATAAACGCCGGTTGGGGAGTATTG
AAACCACCAGTTTAATGAATTTTTATGGACAAGAAGAAAAATACCATACGATAACTGTAAGGGTTCATATCAAAAATTAT
CCTGCAGTTGCCTTTATGATGGCAGTAGTAAATGTGGAACAGTTAGACCGCGCTAATGAACGTTATGAGCGCATTATTAT
TATAGTTATGAGTGTTTTTTGGCTAATTTCTATTTTAGCAAGTATTTATTTAGCCAAGTGGAGCAGAAAACCTATTTTAG
AAAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAATTAAGGACCCCTTTGGCGGTCTTACAGAATCGT
CTGGAATCGCTTTTTCGTAAGCCCAACGAAACGATATTAGAAAATAGTGAGCATCTCGCTTCTAGTTTAGACGAGGTTCG
CAACATGCGCATCTTAACAACTAATTTATTAAATTTAGCAAGACGAGATGATGGCATTAATCCACAGTGGACTCATTTAG
ATACAGATTTTTTTAATGCTATTTTTGAGAATTATGAACTAGTTGCTAAAGAATATGGAAAAATATTTTATTTTCAGAAC
CAAGTCAATAGATCGTTAAGAATGGATAAGGCTTTACTAAAACAATTAATAACGATTTTATTTGACAATGCTATTAAATA
TACAGATAAAAATGGTATTATTGAAATTATAGTGAAAACAACGGACAAAAATTTATTAATTTCTGTTATTGATAATGGTC
CAGGGATAACAGATGAAGAAAAGAAAAAGATTTTTGATCGTTTTTATCGAGTTGACAAAGCTAGAACACGGCAAACAGGT
GGATTTGGCTTGGGGTTGGCTTTAGCTCAGCAAATCGTGATGTCTTTAAAAGGAAATATTACAGTAAAGGATAATGATCC
TAAAGGTAGTATTTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.124

100

0.583
  ciaH Streptococcus pneumoniae Rx1

51.142

100

0.514
  ciaH Streptococcus pneumoniae D39

51.142

100

0.514
  ciaH Streptococcus pneumoniae R6

51.142

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.142

100

0.514