Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   LUA78_RS02465 Genome accession   NZ_CP089283
Coordinates   543089..545065 (-) Length   658 a.a.
NCBI ID   WP_001127900.1    Uniprot ID   Q9ZKA0
Organism   Helicobacter pylori strain J99 derivative isolate D1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 538089..550065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUA78_RS02445 (LUA78_02445) - 538322..539545 (+) 1224 WP_001129865.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  LUA78_RS02450 (LUA78_02450) - 539558..540502 (+) 945 WP_000238176.1 thiamine pyrophosphate-dependent enzyme -
  LUA78_RS02455 (LUA78_02455) purB 540610..541932 (+) 1323 WP_000893867.1 adenylosuccinate lyase -
  LUA78_RS02460 (LUA78_02460) - 542231..543064 (+) 834 WP_000816847.1 outer membrane protein -
  LUA78_RS02465 (LUA78_02465) uvrB 543089..545065 (-) 1977 WP_001127900.1 excinuclease ABC subunit UvrB Machinery gene
  LUA78_RS02470 (LUA78_02470) - 545114..545917 (-) 804 WP_001108919.1 hypothetical protein -
  LUA78_RS02475 (LUA78_02475) - 545914..546346 (-) 433 Protein_478 hypothetical protein -
  LUA78_RS02480 (LUA78_02480) - 546441..549905 (-) 3465 WP_234618126.1 DUF3519 domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75927.29 Da        Isoelectric Point: 6.8347

>NTDB_id=550025 LUA78_RS02465 WP_001127900.1 543089..545065(-) (uvrB) [Helicobacter pylori strain J99 derivative isolate D1]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQTNKPALIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAVKSIEDELALRLKFFKEQDKMLEYNRLKQRTEYDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSQKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKSVVARGERVLITTLTKKMAEELCKYYAEWGLKVRYMHS
EIDAIERNHIIRSLRLKEFDVLIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKTT
QSMQKAFEITSYRRAKQEEFNKIHNITPKTVTRALEEELKLRDDEIKIAKALKKDKMPKSEREKIIKELDKKMRERAKNL
DFEEAMRLRDEIAQLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=550025 LUA78_RS02465 WP_001127900.1 543089..545065(-) (uvrB) [Helicobacter pylori strain J99 derivative isolate D1]
ATGCCTTTATTTGATTTAAAAAGCCCTTATCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCTTTAACGAAAAGCTT
AAAAAATAACAACCATTATCAAACTCTAGTGGGCGTTACAGGGAGCGGTAAGACTTACACGATGGCTAATATCATCGCTC
AAACCAATAAACCCGCTTTGATCATGAGCCATAATAAGACCTTATGCGCGCAACTTTATAGCGAATTTAAGGCGTTTTTC
CCTCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAGAGCTATATCCCTAGGAGGGATTTATT
TATTGAAAAAGACAGCTCTATTAACGATGACTTGGAGCGTTTGAGATTGAGTGCGACCACTTCGCTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTGAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGCTTACAAGAGCTTTTTATTAAAGCTAGTGGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTTAGGGCGACTGGGGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCCTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGGTTGAATTTAGCGGTTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGTATGATTTAG
AAATGATTAGCGCGACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACGGGTAAAGCCCCTAACGAAACG
CCTTTTTGCTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
ACAATTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAGTTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCTCAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCCAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAGATCAAGTCAGTGGTGGCCAGAGGTGAAAGGGTGCTCATCA
CCACGCTCACTAAGAAAATGGCAGAAGAATTGTGCAAGTATTATGCTGAATGGGGCTTGAAGGTGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAATCACATTATCCGCTCTTTAAGGCTTAAGGAATTTGATGTTTTAATAGGGATCAATCT
TTTAAGAGAGGGGCTGGATTTGCCTGAAGTTTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGCG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTACTATACGCTAAAAAAACTACT
CAAAGCATGCAAAAAGCCTTTGAAATCACTAGTTACAGGCGCGCCAAGCAAGAAGAGTTTAATAAAATCCATAACATCAC
CCCCAAAACCGTTACGCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAAATCAAAATCGCTAAAGCTTTAAAAA
AGGACAAAATGCCTAAAAGTGAAAGGGAAAAAATCATTAAAGAATTGGATAAAAAAATGCGAGAGCGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTCAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-248)

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(443-547)

Type III restriction enzyme, res subunit (ResIII)

(15-137)

Ultra-violet resistance protein B (UvrB)

(554-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ZKA0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.774

100

0.502
  uvrB Streptococcus pneumoniae D39

49.774

100

0.502
  uvrB Streptococcus pneumoniae TIGR4

49.774

100

0.502