Detailed information NTG0548978

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: J4Q32_RS09920
• Genome accession: NZ_CP071916
• Coordinates: 1910377..1910679 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413380.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 19A-19087
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1905377..1915679

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4Q32_RS09890 (J4Q32_09880)	rnpA	1906063..1906434 (-)	372	WP_000739246.1	ribonuclease P protein component	-
J4Q32_RS11355	-	1906451..1906582 (-)	132	WP_000768904.1	hypothetical protein	-
J4Q32_RS09895 (J4Q32_09885)	-	1906583..1907773 (-)	1191	WP_000167766.1	acetate kinase	-
J4Q32_RS09900 (J4Q32_09890)	comYH	1907824..1908777 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
J4Q32_RS09905 (J4Q32_09895)	-	1908838..1909425 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
J4Q32_RS09910 (J4Q32_09900)	comGG/cglG	1909562..1909975 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
J4Q32_RS09915 (J4Q32_09905)	comGF/cglF	1909953..1910414 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
J4Q32_RS09920 (J4Q32_09910)	comGE/cglE	1910377..1910679 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
J4Q32_RS09925 (J4Q32_09915)	comGD/cglD	1910642..1911046 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
J4Q32_RS09930 (J4Q32_09920)	comGC/cglC	1911039..1911305 (-)	267	WP_000962026.1	competence type IV pilus major pilin ComGC	Machinery gene
J4Q32_RS09935 (J4Q32_09925)	-	1911307..1911564 (-)	258	WP_000698513.1	hypothetical protein	-
J4Q32_RS09940 (J4Q32_09930)	-	1911796..1912752 (-)	957	WP_233923013.1	N-acetylmuramoyl-L-alanine amidase family protein	-
J4Q32_RS09945 (J4Q32_09935)	-	1912755..1913090 (-)	336	WP_050200954.1	phage holin	-
J4Q32_RS09950 (J4Q32_09940)	-	1913094..1913510 (-)	417	WP_001165344.1	phage holin family protein	-
J4Q32_RS09955 (J4Q32_09945)	-	1913520..1913870 (-)	351	WP_050200952.1	hypothetical protein	-
J4Q32_RS09960 (J4Q32_09950)	-	1913873..1914076 (-)	204	WP_001091109.1	hypothetical protein	-
J4Q32_RS11515	-	1914057..1914173 (-)	117	WP_001063633.1	hypothetical protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11135.11 Da
• Isoelectric Point: 9.7273

>NTDB_id=548978 J4Q32_RS09920 WP_000413380.1 1910377..1910679(-) (comGE/cglE) [Streptococcus pneumoniae strain 19A-19087]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=548978 J4Q32_RS09920 WP_000413380.1 1910377..1910679(-) (comGE/cglE) [Streptococcus pneumoniae strain 19A-19087]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus mitis NCTC 12261	99	100	0.99
comGE/cglE	Streptococcus pneumoniae Rx1	99	100	0.99
comGE/cglE	Streptococcus pneumoniae D39	99	100	0.99
comGE/cglE	Streptococcus pneumoniae R6	99	100	0.99
comGE/cglE	Streptococcus pneumoniae TIGR4	99	100	0.99
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	43.333	90	0.39
comYE	Streptococcus mutans UA159	43.333	90	0.39