Detailed information NTG0548960

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: J4Q32_RS08805
• Genome accession: NZ_CP071916
• Coordinates: 1720488..1721555 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159553.1
• Uniprot ID: A0A0T8CF10
• Organism: Streptococcus pneumoniae strain 19A-19087
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1715488..1726555

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4Q32_RS08780 (J4Q32_08785)	treR	1715575..1716285 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
J4Q32_RS08785 (J4Q32_08790)	-	1716442..1717585 (+)	1144	Protein_1758	transposase	-
J4Q32_RS08790 (J4Q32_08795)	-	1717752..1719098 (+)	1347	WP_001814919.1	IS1380-like element ISSpn5 family transposase	-
J4Q32_RS08795 (J4Q32_08800)	-	1719291..1719476 (+)	186	Protein_1760	transposase	-
J4Q32_RS08800 (J4Q32_08805)	amiF	1719551..1720477 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
J4Q32_RS08805 (J4Q32_08810)	amiE	1720488..1721555 (-)	1068	WP_000159553.1	ABC transporter ATP-binding protein	Regulator
J4Q32_RS08810 (J4Q32_08815)	amiD	1721564..1722490 (-)	927	WP_000103702.1	oligopeptide ABC transporter permease OppC	Regulator
J4Q32_RS08815 (J4Q32_08820)	amiC	1722490..1723986 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
J4Q32_RS08820 (J4Q32_08825)	amiA3	1724053..1726032 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39437.04 Da
• Isoelectric Point: 4.8002

>NTDB_id=548960 J4Q32_RS08805 WP_000159553.1 1720488..1721555(-) (amiE) [Streptococcus pneumoniae strain 19A-19087]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=548960 J4Q32_RS08805 WP_000159553.1 1720488..1721555(-) (amiE) [Streptococcus pneumoniae strain 19A-19087]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0T8CF10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.761	100	0.868
amiE	Streptococcus thermophilus LMD-9	86.761	100	0.868
oppD	Streptococcus mutans UA159	54.545	99.155	0.541